⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4023693 | 0.95 | TSHR (0.32) | — | |
| SCHEMBL10123519 | 0.95 | TSHR (0.32) | — | |
| SCHEMBL16087240 | 0.83 | — | — | |
| SCHEMBL252263 | 0.80 | DHODH (0.45) | — | |
| SCHEMBL18757668 | 0.79 | — | — | |
| SCHEMBL4363694 | 0.78 | — | — | |
| SCHEMBL8197869 | 0.77 | KDM4E (0.38) | — | |
| SCHEMBL14081363 | 0.77 | KDM4E (0.38) | — | |
| SCHEMBL18535196 | 0.77 | — | — | |
| SCHEMBL11406762 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111995586-B | Synthetic method of agricultural herbicide | 蚌埠学院 | 2023-03-21 | — | — | CN | claimed |
| CN-111995586-A | Synthetic method of agricultural herbicide | 蚌埠学院 | 2020-11-27 | — | — | CN | claimed |
| EP-1781339-A1 | COMPOUNDS OF THE INVENTIONS OF GUANYLYL CYCLASE C | THOMAS JEFFERSON UNIVERSITY (US) | 2007-05-09 | — | — | EP | claimed |
| WO-2006012264-A1 | COMPOUNDS OF THE INVENTIONS OF GUANYLYL CYCLASE C | THOMAS JEFFERSON UNIVERSITY (US) | 2006-02-02 | — | — | WO | claimed |
| US-20050287067-A1 | Compounds of the inventions of guanylyl cyclase C | THOMAS JEFFERSON UNIVERSITY | 2005-12-29 | — | — | US | claimed |
| CN-111995586-B | Synthetic method of agricultural herbicide | 蚌埠学院 | 2023-03-21 | — | — | CN | disclosed |
| CN-111995586-B | Synthetic method of agricultural herbicide | 蚌埠学院 | 2023-03-21 | — | — | CN | disclosed |
| CN-111995586-A | Synthetic method of agricultural herbicide | 蚌埠学院 | 2020-11-27 | — | — | CN | disclosed |
| CN-111995586-A | Synthetic method of agricultural herbicide | 蚌埠学院 | 2020-11-27 | — | — | CN | disclosed |
| US-9447146-B2 | Guanylylcyclase C ligands | THOMAS JEFFERSON UNIVERSITY (US) | 2016-09-20 | — | — | US | disclosed |
| US-20140147380-A1 | GUANYLYLCYCLASE C LIGANDS | THOMAS JEFFERSON UNIVERSITY (US) | 2014-05-29 | — | — | US | disclosed |
| EP-2722060-A2 | Guanylyl cyclase C ligands | Thomas Jefferson University (US) | 2014-04-23 | — | — | EP | disclosed |
| WO-2005044264-A1 | CCR-2 ANTAGONIST SALT | MERCK & CO., INC. (US) | 2005-05-19 | — | — | WO | disclosed |
| US-20040142949-A1 | Compounds, compositions, and methods | CYTOKINETICS, INC. | 2004-07-22 | — | — | US | disclosed |
| WO-2004034972-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2004-04-29 | — | — | WO | disclosed |
| CN-1479724-A | Pyridone derivatives for the treatment of atherosclerosis | ʷ��˿�������ȳ�ķ����˾ | 2004-03-03 | — | — | CN | disclosed |
| WO-2004009036-A2 | COMPOUNDS COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2004-01-29 | — | — | WO | disclosed |
| US-6147254-A | Process for resolving mixtures of carbocyclic stereoisomers | GLAXO WELLCOME INC. (US) | 2000-11-14 | — | — | US | disclosed |
| EP-0946496-A2 | PROCESS FOR RESOLVING MIXTURES OF CARBOCYCLIC STEREOISOMERS | GLAXO GROUP LIMITED (GB) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024741-A2 | PROCESS FOR RESOLVING MIXTURES OF CARBOCYCLIC STEREOISOMERS | GLAXO GROUP LIMITED (GB) | 1998-06-11 | — | — | WO | disclosed |