Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | NEK2 | P51955 | 2/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 6/20 | 0.33 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.33 |
| ▸ | ABL1 | P00519 | 3/20 | 0.33 |
| ▸ | CSF1R | P07333 | 3/20 | 0.33 |
| ▸ | LYN | P07948 | 3/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.33 |
| ▸ | TGFBR2 | P37173 | 3/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.33 |
| ▸ | SIK1 | P57059 | 3/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.33 |
| ▸ | SIK2 | Q9H0K1 | 3/20 | 0.33 |
| ▸ | SIK3 | Q9Y2K2 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22092061 | 0.94 | PRMT5 (0.39) | CHRM1PDK2FGFR3PRMT5WDR77 | |
| Trifluoroacetic Acid SCHEMBL22092139 | 0.81 | MCHR1 (0.35) | GPR139 | |
| Trifluoroacetic Acid SCHEMBL22092031 | 0.81 | FLT3 (0.38) | FLT3GPR139 | |
| Trifluoroacetic Acid SCHEMBL22092166 | 0.80 | GPR139 (0.34) | FGFR3GPR139PRKAG1PRKAA1 | |
| Trifluoroacetic Acid SCHEMBL22091147 | 0.80 | PPARD (0.37) | CHRM1PDK2PRMT5WDR77ACSS2 | |
| Trifluoroacetic Acid SCHEMBL22091226 | 0.79 | COMT (0.36) | CHRM1PDK2PRMT5WDR77FLT3 | |
| Trifluoroacetic Acid SCHEMBL22091157 | 0.79 | CHRM1 (0.43) | CHRM1PDK2PRMT5WDR77ACSS2 | |
| Trifluoroacetic Acid SCHEMBL22092064 | 0.79 | GPR139 (0.36) | GPR139 | |
| Trifluoroacetic Acid SCHEMBL22206411 | 0.78 | GRM2 (0.38) | GPR139 | |
| Trifluoroacetic Acid SCHEMBL22091212 | 0.78 | CREBBP (0.40) | CHRM1PDK2PRMT5WDR77ACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820769-B2 | Triazolopyridin-3-ones or their salts and pharmaceutical compositions comprising the same | YUHAN CORPORATION (KR) | 2023-11-21 | — | — | US | disclosed |
| US-20220024918-A1 | TRIAZOLOPYRIDIN-3-ONES OR THEIR SALTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | YUHAN CORPORATION (KR) | 2022-01-27 | — | — | US | disclosed |
| EP-3894408-A1 | TRIAZOLOPYRIDIN-3-ONES OR THEIR SALTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Yuhan Corporation (KR) | 2021-10-20 | — | — | EP | disclosed |
| US-11091479-B2 | Triazolopyridin-3-ones or their salts and pharmaceutical compositions comprising the same | YUHAN CORPORATION (KR) | 2021-08-17 | — | — | US | disclosed |
| US-20200223844-A1 | TRIAZOLOPYRIDIN-3-ONES OR THEIR SALTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | YUHAN CORPORATION (KR) | 2020-07-16 | — | — | US | disclosed |
| WO-2020121263-A1 | TRIAZOLOPYRIDIN-3-ONES OR THEIR SALTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | YUHAN CORPORATION (KR) | 2020-06-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11091479-B2 | Triazolopyridin-3-ones or their salts and pharmaceutical compositions comprising the same | VAPB, HDLBP, VAPA | CHRM1 1445/4885PDK2 2032/4885FGFR3 3896/4885 |
| US-11820769-B2 | Triazolopyridin-3-ones or their salts and pharmaceutical compositions comprising the same | VAPB, HDLBP, VAPA | CHRM1 1445/4885PDK2 2032/4885FGFR3 3896/4885 |
| US-20200223844-A1 | TRIAZOLOPYRIDIN-3-ONES OR THEIR SALTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | VAPB, HDLBP, VAPA | CHRM1 1445/4885PDK2 2032/4885FGFR3 3896/4885 |
| US-20220024918-A1 | TRIAZOLOPYRIDIN-3-ONES OR THEIR SALTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | VAPB, HDLBP, VAPA | CHRM1 1445/4885PDK2 2032/4885FGFR3 3896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.