Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 13/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22206423 | 0.85 | GPR139 (0.46) | GPR139PDE10AKDM4ENPC1RXFP1 | |
| SCHEMBL22206303 | 0.82 | GPR139 (0.47) | GPR139PDE10AKDM4ERXFP1SLC5A1 | |
| Hydrochloric Acid SCHEMBL22206372 | 0.81 | GPR139 (0.47) | GPR139PDE10AKDM4ESLC5A1SLC5A2 | |
| SCHEMBL22206320 | 0.80 | GPR139 (0.37) | GPR139KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL22206319 | 0.80 | GPR139 (0.37) | GPR139KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL17141321 | 0.76 | GPR139 (0.58) | GPR139PDE10AKDM4ENPC1ALDH1A1 | |
| SCHEMBL21382520 | 0.74 | PPARD (0.45) | — | |
| SCHEMBL21382411 | 0.74 | PPARD (0.45) | — | |
| SCHEMBL21382415 | 0.74 | PPARD (0.45) | — | |
| SCHEMBL17141252 | 0.71 | GPR139 (0.56) | GPR139PDE10AKDM4EALDH1A1SLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3894408-A1 | TRIAZOLOPYRIDIN-3-ONES OR THEIR SALTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Yuhan Corporation (KR) | 2021-10-20 | — | — | EP | disclosed |
| WO-2020121263-A1 | TRIAZOLOPYRIDIN-3-ONES OR THEIR SALTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | YUHAN CORPORATION (KR) | 2020-06-18 | — | — | WO | disclosed |