Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22092214 | 0.93 | AKR1B1 (0.52) | CES1CES2ALDH1A1AKR1B1GPR84 | |
| SCHEMBL22092351 | 0.91 | GPR84 (0.54) | CES1CES2ALDH1A1AKR1B1GPR84 | |
| SCHEMBL17386431 | 0.90 | CES1 (0.50) | CES1CES2ALDH1A1AKR1B1TP53 | |
| SCHEMBL26688788 | 0.85 | FFAR3 (0.46) | CES1CES2ALDH1A1AKR1B1GPR84 | |
| SCHEMBL11020077 | 0.83 | AKR1B1 (0.56) | CES1CES2ALDH1A1AKR1B1GPR84 | |
| SCHEMBL22227521 | 0.81 | GPR84 (0.58) | CES1CES2ALDH1A1AKR1B1GPR84 | |
| SCHEMBL8667616 | 0.81 | GPR84 (0.58) | CES1CES2ALDH1A1AKR1B1GPR84 | |
| SCHEMBL28637199 | 0.81 | GPR84 (0.58) | CES1CES2ALDH1A1AKR1B1GPR84 | |
| SCHEMBL28616917 | 0.81 | GPR84 (0.58) | CES1CES2ALDH1A1AKR1B1GPR84 | |
| SCHEMBL3870298 | 0.79 | FNTA (0.50) | CES1CES2ALDH1A1AKR1B1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191530-B1 | SOLUTION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, SOLUTION POLYMERIZATION METHODS, AND POLYMER COMPOSITIONS | SIRRUS INC (US) | 2020-11-11 | — | — | EP | claimed |
| EP-3191546-B1 | EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS | SIRRUS INC (US) | 2020-07-22 | — | — | EP | claimed |
| US-20210309780-A1 | METHYLENE MALONATE MONOMERS AND MULTIFUNCTIONAL MACROMERS AS ADDITIVES DURING PLASTICS PROCESSING | SIRRUS, INC. | 2021-10-07 | — | — | US | disclosed |
| WO-2020123579-A1 | POLYMERIZATION OF 1,1-DICARBONYL 1-ALKENES | SIRRUS, INC. (US) | 2020-06-18 | — | — | WO | disclosed |
| WO-2020123581-A1 | EMULSION POLYMERS OF 1,1-DICARBONYL 1-ALKENES OF CONTROLLED PARTICLE SIZE | SIRRUS, INC. (US) | 2020-06-18 | — | — | WO | disclosed |