Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.64 |
| ▸ | STAT3 | P40763 | 1/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30377496 | 0.89 | TYK2 (0.70) | TYK2STAT3PDE4D | |
| SCHEMBL22092666 | 0.89 | TYK2 (0.70) | TYK2STAT3PDE4D | |
| SCHEMBL22103744 | 0.87 | TYK2 (0.73) | TYK2STAT3PDE4D | |
| SCHEMBL30378065 | 0.86 | TYK2 (0.50) | TYK2STAT3PDE4D | |
| SCHEMBL22103745 | 0.84 | TYK2 (0.63) | TYK2STAT3 | |
| SCHEMBL29746781 | 0.83 | TYK2 (0.79) | TYK2STAT3PDE4D | |
| SCHEMBL22342924 | 0.83 | TYK2 (0.79) | TYK2STAT3PDE4D | |
| SCHEMBL23327531 | 0.82 | TYK2 (0.62) | TYK2STAT3PDE4D | |
| SCHEMBL30548465 | 0.82 | TYK2 (0.62) | TYK2STAT3PDE4D | |
| SCHEMBL22342927 | 0.82 | TYK2 (0.65) | TYK2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166163-B | 7- (methylamino) pyrazolo [1,5-A ] pyrimidine-3-carboxamide derivatives | 伊莱利利公司 | 2023-04-07 | — | — | CN | disclosed |
| EP-3894412-B1 | 7-(METHYLAMINO)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE DERIVATIVES | LILLY CO ELI (US) | 2023-02-08 | — | — | EP | disclosed |
| US-20220024933-A1 | 7 (METHYLAMINO)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE DERIVATIVES | ELI LILLY AND COMPANY | 2022-01-27 | — | — | US | disclosed |
| EP-3894412-A1 | 7-(METHYLAMINO)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE DERIVATIVES | Eli Lilly and Company (US) | 2021-10-20 | — | — | EP | disclosed |
| WO-2020123225-A1 | 7-(METHYLAMINO)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2020-06-18 | — | — | WO | disclosed |
| WO-2020123225-A1 | 7-(METHYLAMINO)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2020-06-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220024933-A1 | 7 (METHYLAMINO)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE DERIVATIVES | SSB, TLR7, TPMT | TYK2 57/4885STAT3 207/4885PDE4D 837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.