Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 11/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30378401 | 0.92 | TYK2 (0.53) | TYK2STAT3ADORA3ADORA2AADORA1 | |
| SCHEMBL22092687 | 0.86 | TYK2 (0.64) | TYK2STAT3PDE4D | |
| SCHEMBL22092677 | 0.86 | TYK2 (0.44) | TYK2STAT3ADORA3ADORA2AADORA2B | |
| SCHEMBL30349340 | 0.83 | ADORA3 (0.48) | TYK2STAT3ADORA3ADORA2AADORA2B | |
| SCHEMBL28641308 | 0.83 | TYK2 (0.76) | TYK2STAT3 | |
| SCHEMBL22092672 | 0.77 | TYK2 (0.47) | TYK2STAT3ADORA3ADORA2AADORA1 | |
| SCHEMBL30349310 | 0.77 | CCNA2 (0.54) | ADORA3ADORA2AADORA2BADORA1GAA | |
| SCHEMBL22092666 | 0.76 | TYK2 (0.70) | TYK2STAT3PDE4D | |
| SCHEMBL30377496 | 0.76 | TYK2 (0.70) | TYK2STAT3PDE4D | |
| SCHEMBL22103866 | 0.75 | TYK2 (0.45) | TYK2STAT3GAAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166163-B | 7- (methylamino) pyrazolo [1,5-A ] pyrimidine-3-carboxamide derivatives | 伊莱利利公司 | 2023-04-07 | — | — | CN | disclosed |