SCHEMBL22096277

SCHEMBL22096277

CCC(CC)COC(=O)[C@H](C)NP(=O)(N[C@@H](C)C(=O)OCC(CC)CC)OC[C@@H]1CC[C@](C#N)(c2ccc3c(N)ncnn23)O1

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ AXL P30530 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22739004 0.95 — —
SCHEMBL22393573 0.92 TMPRSS2 (0.32) —
SCHEMBL24148708 0.90 CYP3A4 (0.32) —
SCHEMBL18636608 0.90 CYP3A4 (0.32) —
SCHEMBL25012912 0.87 CSNK1A1 (0.31) —
SCHEMBL18636474 0.87 TMPRSS2 (0.31) —
SCHEMBL25012546 0.86 — —
SCHEMBL22096270 0.83 TMPRSS2 (0.44) —
SCHEMBL10142401 0.82 TMPRSS2 (0.33) —
SCHEMBL14845671 0.82 TMPRSS2 (0.33) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10682368-B2 Methods of treating feline coronavirus infections GILEAD SCIENCES, INC. (US) 2020-06-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10682368-B2 Methods of treating feline coronavirus infections SARS1, CPN1, CAT AXL 3687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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