Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 15/20 | 0.74 |
| ▸ | CYP4F2 | P78329 | 13/20 | 0.74 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | SCN4A | P35499 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22098283 | 0.97 | CYP4A11 (0.75) | CYP4A11CYP4F2NPC1LTA4HSCN4A | |
| SCHEMBL23309388 | 0.85 | CYP4A11 (1.00) | CYP4A11CYP4F2 | |
| SCHEMBL22098270 | 0.83 | CYP4F2 (0.61) | CYP4A11CYP4F2FFAR4 | |
| SCHEMBL23309265 | 0.82 | CYP4A11 (1.00) | CYP4A11CYP4F2 | |
| SCHEMBL22098365 | 0.80 | CYP4F2 (0.73) | CYP4A11CYP4F2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL23309229 | 0.80 | CYP4A11 (1.00) | CYP4A11CYP4F2 | |
| SCHEMBL30903818 | 0.76 | SCN4A (0.64) | CYP4A11CYP4F2NPC1LTA4HSCN4A | |
| SCHEMBL23309198 | 0.73 | CYP4A11 (1.00) | CYP4A11CYP4F2 | |
| SCHEMBL15918403 | 0.72 | LTA4H (0.72) | CYP4A11CYP4F2NPC1LTA4HSCN4A | |
| SCHEMBL23309331 | 0.72 | CYP4A11 (1.00) | CYP4A11CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666766-A1 | PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE | Taisho Pharmaceutical Co., Ltd. (JP) | 2020-06-17 | — | — | EP | disclosed |