Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 18/20 | 0.58 |
| ▸ | CYP4A11 | Q02928 | 18/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20730306 | 0.80 | CYP4F2 (0.77) | CYP4F2CYP4A11CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL23309269 | 0.73 | CYP4F2 (1.00) | CYP4F2CYP4A11 | |
| SCHEMBL22098432 | 0.68 | CYP4F2 (0.76) | CYP4F2CYP4A11CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22098365 | 0.68 | CYP4F2 (0.73) | CYP4F2CYP4A11CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL23309275 | 0.68 | CYP4F2 (1.00) | CYP4F2CYP4A11 | |
| SCHEMBL23309455 | 0.68 | CYP4F2 (1.00) | CYP4F2CYP4A11 | |
| SCHEMBL14653855 | 0.67 | LTA4H (0.68) | CYP4F2CYP4A11CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22098548 | 0.66 | CYP4F2 (0.80) | CYP4F2CYP4A11 | |
| SCHEMBL14129967 | 0.65 | CYP1A2 (0.62) | CYP4F2CYP4A11CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14653751 | 0.64 | CYP3A4 (0.61) | CYP4F2CYP4A11CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666766-A1 | PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE | Taisho Pharmaceutical Co., Ltd. (JP) | 2020-06-17 | — | — | EP | disclosed |