SCHEMBL220987

SCHEMBL220987

Brc1[c]occ1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1727698 0.65
SCHEMBL6905759 0.63
SCHEMBL277548 0.62
SCHEMBL49776 0.62
SCHEMBL5256 0.62
SCHEMBL3651286 0.61
SCHEMBL275794 0.57
SCHEMBL3243826 0.57
SCHEMBL1768412 0.57
SCHEMBL467306 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116199643-A Phenothiazine compound containing isopropanol substructure, and preparation and application thereof 贵州大学 2023-06-02 CN claimed
CN-116041308-A Seven-membered cyclic saccharide compound, and preparation method and application thereof 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) 2023-05-02 CN claimed
CN-113461634-A Thiazole hydrazide compounds and preparation method and application thereof 贵州大学 2021-10-01 CN claimed
EP-2782565-B1 USE OF ARYL AND HETARYL CARBOXAMIDES AS ENDOPARASITICIDES BAYER IP GMBH (DE) 2019-11-06 EP claimed
CN-110381963-A It is related to the immunotherapy method and composition of tryptophan metabolic pathway regulator 朱诺治疗学股份有限公司 2019-10-25 CN claimed
CN-110078659-A A kind of isodextropimaric acid heterocycle acylhydrazone and its preparation method and application 中国林业科学研究院林产化学工业研究所 2019-08-02 CN claimed
CN-109776592-A Pyrrolo-pyrrole-dione borate and the method for detecting fluorine ion with it 南京信息工程大学 2019-05-21 CN claimed
CN-104042611-B 1 of inhibitor as indoleamine 2,3-dioxygenase, 2,5- oxadiazoles 因塞特控股公司 2019-05-14 CN claimed
US-20180179193-A1 N-Sulfonyl Homoserine Lactone Derivatives, Preparation Method and Use Thereof INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA (CN) 2018-06-28 US claimed
EP-2920163-B1 PYRIDYLOXYAL ALKYL CARBOXAMIDES AND THEIR USE AS ENDOPARASITICIDES AND NEMATICIDE BAYER CROPSCIENCE AG (DE) 2018-05-02 EP claimed
EP-1910362-A1 IMIDAZOPYRIDINE DERIVATIVES AS SIRTUIN MODULATING AGENTS Sirtris Pharmaceuticals, Inc. (US) 2008-04-16 EP claimed
US-20070037827-A1 Silent Information Regulators; aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting , increased mitochondrial activity, inflammation, cancer, and/or flushing; increased lifespan specially in mutant sir2 strains; imidazo[1,2-a]pyridine drivatives SIRTRIS PHARMACEUTICALS, INC. (US) 2007-02-15 US claimed
WO-2007019345-A1 IMIDAZOPYRIDINE DERIVATIVES AS SIRTUIN MODULATING AGENTS SIRTRIS PHARMACEUTICALS, INC. (US) 2007-02-15 WO claimed
EP-1140802-B1 SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES BOEHRINGER INGELHEIM PHARMA (DE) 2004-03-17 EP claimed
US-20040023972-A1 Use of substituted imidazo[1,2-a]-pyridin-, -pyrimidin-and-pyrazin-3-yl-amine derivatives in the preparation of medicaments for inhibiting NOS GRUENENTHAL GMBH (DE) 2004-02-05 US claimed
EP-1326613-A1 USE OF SUBSTITUTED IMIDAZO 1,2-A]PYRIDINE-, IMIDAZO 1,2-A]PYRIMIDINE AND IMIDAZO 1,2-A]PYRAZINE-3-YL-AMINE DERIVATIVES FOR PRODUCING NOS-INHIBITING MEDICAMENTS Grünenthal GmbH (DE) 2003-07-16 EP claimed
WO-2002030428-A1 USE OF SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE-, IMIDAZO[1,2-A]PYRIMIDINE AND IMIDAZO[1,2-A]PYRAZINE-3-YL-AMINE DERIVATIVES FOR PRODUCING NOS-INHIBITING MEDICAMENTS Grünenthal GmbH (DE) 2002-04-18 WO claimed
EP-0846686-B1 1-Phenyl-pyrazol derivatives and their use as parasiticidal agents PFIZER LTD (GB) 2002-01-09 EP claimed
US-6069157-A Parasiticidal compounds PFIZER INC. (US) 2000-05-30 US claimed
EP-0846686-A1 1-Phenyl-pyrazol derivatives and their use as parasiticidal agents Pfizer Limited (GB) 1998-06-10 EP claimed