SCHEMBL49776

SCHEMBL49776

Oc1[c]occ1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1727698 0.65
SCHEMBL11456086 0.64 ESR1 (0.43)
SCHEMBL1768412 0.63
SCHEMBL5256 0.62
SCHEMBL220987 0.62
SCHEMBL277548 0.62
SCHEMBL3651286 0.61
SCHEMBL8914404 0.60
SCHEMBL11437332 0.60
SCHEMBL7198316 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116199643-A Phenothiazine compound containing isopropanol substructure, and preparation and application thereof 贵州大学 2023-06-02 CN claimed
CN-116041308-A Seven-membered cyclic saccharide compound, and preparation method and application thereof 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) 2023-05-02 CN claimed
CN-110713588-B Hardmask composition, hardmask layer and method of forming pattern 三星SDI株式会社 2022-08-09 CN claimed
CN-114181148-A 'on-off' type fluorescent probe, preparation method and application thereof 东北农业大学 2022-03-15 CN claimed
US-11214678-B2 Hardmask composition, hardmask layer and method of forming patterns SAMSUNG SDI CO., LTD. (KR) 2022-01-04 US claimed
CN-110713588-A Hardmask composition, hardmask layer and method of forming pattern 三星SDI株式会社 2020-01-21 CN claimed
CN-110078721-A Dioctyl glutaricate and its preparation method and application of the one kind containing triazine 贵州大学 2019-08-02 CN claimed
CN-109721554-A A kind of 4- amino-quinazoline compound and its preparation method and application 贵州大学 2019-05-07 CN claimed
CN-109535144-A A kind of 1,3,4- oxadiazoles thio-ether type compounds and its preparation method and application 贵州大学 2019-03-29 CN claimed
EP-2428577-B1 Preparation of tyrosinase-inhibiting hydroxybenzyl and hydroxypyranonemethyl esters EASTMAN CHEM CO (US) 2014-01-22 EP claimed
EP-2428577-A1 Preparation of tyrosinase-inhibiting hydroxybenzyl and hydroxypyranonemethyl esters EASTMAN CHEMICAL COMPANY (US) 2012-03-14 EP claimed
US-20110129430-A1 HYDROXYBENZYL OR HYDROXYPYRANONEMETHYL ESTERS AS TYROSINASE INHIBITORS EASTMAN CHEMICAL COMPANY (US) 2011-06-02 US claimed
EP-2155886-A2 HYDROXYBENZYL OR HYDROXYPYRANONEMETHYL ESTERS AS TYROSINASE INHIBITORS Eastman Chemical Company (US) 2010-02-24 EP claimed
WO-2008153784-A2 HYDROXYBENZYL OR HYDROXYPYRANONEMETHYL ESTERS AS TYROSINASE INHIBITORS EASTMAN CHEMICAL COMPANY (US) 2008-12-18 WO claimed
US-20080306144-A1 Hydroxybenzyl or hydroxypyranonemethyl esters as tyrosinase inhibitors EASTMAN CHEMICAL COMPANY 2008-12-11 US claimed
WO-2008143777-A1 HYDROQUINONE DERIVATIVE SKIN BRIGHTENING COMPOUNDS EASTMAN CHEMICAL COMPANY (US) 2008-11-27 WO claimed
US-20080286219-A1 Hydroquinone derivative skin brightening compounds EASTMAN CHEMICAL COMPANY 2008-11-20 US claimed
EP-0973768-A1 AZOLE COMPOUNDS, THEIR PRODUCTION AND THEIR USE Takeda Chemical Industries, Ltd. (JP) 2000-01-26 EP claimed
WO-1998043970-A1 AZOLE COMPOUNDS, THEIR PRODUCTION AND THEIR USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-10-08 WO claimed
US-20240045330-A1 NEGATIVE PHOTOSENSITIVE COMPOSITION AND PATTERN FORMATION METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2024-02-08 US disclosed
CN-117486770-A 2-cyanoacrylate compound and preparation method and application thereof 贵州大学 2024-02-02 CN disclosed
CN-117420731-A Negative photosensitive composition and pattern forming method 东京应化工业株式会社 2024-01-19 CN disclosed
CN-113286781-B Sulfonium salt, photoacid generator, curable composition, and resist composition 三亚普罗股份有限公司 2023-08-08 CN disclosed
US-20230236505-A1 NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMATION METHOD, AND LAMINATED FILM SAN-APRO LTD. (JP) 2023-07-27 US disclosed
CN-113461634-B Thiazole hydrazide compound and preparation method and application thereof 贵州大学 2023-07-04 CN disclosed
CN-116199643-A Phenothiazine compound containing isopropanol substructure, and preparation and application thereof 贵州大学 2023-06-02 CN disclosed
CN-116018558-A Negative photosensitive resin composition, pattern forming method and laminated film 三亚普罗股份有限公司 2023-04-25 CN disclosed
CN-115542666-A Photosensitive resin composition for spacer and protective film 奇美实业股份有限公司 2022-12-30 CN disclosed
CN-110713588-B Hardmask composition, hardmask layer and method of forming pattern 三星SDI株式会社 2022-08-09 CN disclosed
CN-114181148-B 'on-off' type fluorescent probe, preparation method and application thereof 东北农业大学 2022-08-05 CN disclosed
CN-110078721-B Triazine-containing pentadiene ketone compound and preparation method and application thereof 贵州大学 2022-03-25 CN disclosed
CN-114181148-A 'on-off' type fluorescent probe, preparation method and application thereof 东北农业大学 2022-03-15 CN disclosed
US-11214678-B2 Hardmask composition, hardmask layer and method of forming patterns SAMSUNG SDI CO., LTD. (KR) 2022-01-04 US disclosed
EP-3909943-A1 SULFONIUM SALT, PHOTOACID GENERATOR, CURABLE COMPOSITION AND RESIST COMPOSITION San-Apro Ltd. (JP) 2021-11-17 EP disclosed
CN-113620894-A Oxadiazole thioether compounds containing amide substructure as well as preparation method and application thereof 贵州大学 2021-11-09 CN disclosed
CN-113461634-A Thiazole hydrazide compounds and preparation method and application thereof 贵州大学 2021-10-01 CN disclosed
CN-113286781-A Sulfonium salt, photoacid generator, curable composition, and resist composition 三亚普罗股份有限公司 2021-08-20 CN disclosed
WO-2020145043-A1 SULFONIUM SALT, PHOTOACID GENERATOR, CURABLE COMPOSITION AND RESIST COMPOSITION サンアプロ株式会社 2020-07-16 WO disclosed
CN-111393359-A Pyridine salt-containing N- (cinnamoyl) -N' - (substituted) propyl hydrazide compound and preparation method and application thereof 贵州大学 2020-07-10 CN disclosed
CN-110713588-A Hardmask composition, hardmask layer and method of forming pattern 三星SDI株式会社 2020-01-21 CN disclosed
CN-110078721-A Dioctyl glutaricate and its preparation method and application of the one kind containing triazine 贵州大学 2019-08-02 CN disclosed
CN-106659161-B Amide compound and its harmful arthropod prevent and kill off purposes 住友化学株式会社 2019-08-02 CN disclosed
CN-109721554-A A kind of 4- amino-quinazoline compound and its preparation method and application 贵州大学 2019-05-07 CN disclosed
US-10251396-B2 Amide compound and use of same for noxious arthropod control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-04-09 US disclosed
CN-109535144-A A kind of 1,3,4- oxadiazoles thio-ether type compounds and its preparation method and application 贵州大学 2019-03-29 CN disclosed
CN-105873911-B Thiazolium compounds and its Pesticidal purposes 住友化学株式会社 2018-07-24 CN disclosed
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
US-20170295789-A1 AMIDE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-10-19 US disclosed
US-9730449-B2 Thiazole compound and its use in pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-15 US disclosed
EP-3178322-A1 AMIDE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL Sumitomo Chemical Company Limited (JP) 2017-06-14 EP disclosed
CN-106659161-A Amide compound and use of same for noxious arthropod control 住友化学株式会社 2017-05-10 CN disclosed
CN-104955332-B The method of preventing and treating arthropod insect 住友化学株式会社 2017-03-29 CN disclosed
EP-3093286-A1 THIAZOLE COMPOUNDS AND PEST CONTROL APPLICATIONS THEREOF Sumitomo Chemical Co., Ltd (JP) 2016-11-16 EP disclosed
US-20160324155-A1 THIAZOLE COMPOUND AND ITS USE IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-11-10 US disclosed
CN-105873911-A Thiazole compounds and pest control applications thereof 住友化学株式会社 2016-08-17 CN disclosed
EP-2952096-A1 METHOD FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2015-12-09 EP disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed
CN-104955332-A Method for controlling arthropod pest SUMITOMO CHEMICAL CO 2015-09-30 CN disclosed
US-20150005348-A1 AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-01-01 US disclosed
EP-2813492-A1 AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL Sumitomo Chemical Co., Ltd (JP) 2014-12-17 EP disclosed
CN-104105694-A Amide compound and use thereof for pest control SUMITOMO CHEMICAL CO 2014-10-15 CN disclosed
EP-2428577-B1 Preparation of tyrosinase-inhibiting hydroxybenzyl and hydroxypyranonemethyl esters EASTMAN CHEM CO (US) 2014-01-22 EP disclosed
EP-2284165-B1 SULFONIUM SALT, PHOTOACID GENERATOR, PHOTO-CURABLE COMPOSITION, AND CURED PRODUCT OF THE PHOTO-CURABLE COMPOSITION SAN APRO LTD (JP) 2013-02-20 EP disclosed
CN-102712587-A Novel ethane diamine hepcidin antagonists VIFOR INT AG 2012-10-03 CN disclosed
US-8278030-B2 Sulfonium salt, photoacid generator, and photocurable composition and cured body thereof SAN-APRO LIMITED (JP) 2012-10-02 US disclosed
EP-2428577-A1 Preparation of tyrosinase-inhibiting hydroxybenzyl and hydroxypyranonemethyl esters EASTMAN CHEMICAL COMPANY (US) 2012-03-14 EP disclosed
EP-2155886-B1 Cosmetic use of inhibitors of tyrosinase EASTMAN CHEM CO (US) 2012-03-07 EP disclosed
US-8129467-B2 Curing accelerating compound-silica composite material, method for producing curing accelerating compound-silica composite material, curing accelerator, curable resin composition, and electronic component device HITACHI CHEMICAL CO., LTD. (JP) 2012-03-06 US disclosed
US-8013052-B2 Curable resin, production method thereof, epoxy resin composition, and electronic device HITACHI CHEMICAL COMPANY, LTD. (JP) 2011-09-06 US disclosed
US-20110129430-A1 HYDROXYBENZYL OR HYDROXYPYRANONEMETHYL ESTERS AS TYROSINASE INHIBITORS EASTMAN CHEMICAL COMPANY (US) 2011-06-02 US disclosed
US-20110039205-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOCURABLE COMPOSITION AND CURED BODY THEREOF SAN-APRO LIMITED (JP) 2011-02-17 US disclosed
EP-2284165-A1 PHOSPHONIUM SALT, PHOTOACID GENERATOR, PHOTO-CURABLE COMPOSITION, AND CURED PRODUCT OF THE PHOTO-CURABLE COMPOSITION San-Apro Limited (JP) 2011-02-16 EP disclosed
EP-1994011-B1 SULFONYL BENZIMIDAZOLE DERIVATIVES RAQUALIA PHARMA INC (JP) 2010-10-13 EP disclosed
US-20100240908-A1 ACETYLENE COMPOUND FUJIFILM CORPORATION (JP) 2010-09-23 US disclosed
EP-2202221-A1 ACETYLENE COMPOUND Fujifilm Corporation (JP) 2010-06-30 EP disclosed
US-7700618-B2 Sulfonyl benzimidazole derivatives PFIZER INC (US) 2010-04-20 US disclosed
EP-2155886-A2 HYDROXYBENZYL OR HYDROXYPYRANONEMETHYL ESTERS AS TYROSINASE INHIBITORS Eastman Chemical Company (US) 2010-02-24 EP disclosed
US-7666953-B2 Phosphine-protonated haloaromatic compound accelerator with curing resin and curing agent HITACHI CHEMICAL CO, LTD. (JP) 2010-02-23 US disclosed
US-7598393-B2 Sulfonyl benzimidazole derivatives PFIZER INC. (US) 2009-10-06 US disclosed
US-7585904-B2 Curing accelerator comprising a reaction product of an intramolecular phosphonium salt and a silanol compound; suitable as a material for laminates and adhesives and an electronic parts device comprising an element that has been encapsulated using such a curable resin composition HITACHI CHEMICAL COMPANY, LTD. (JP) 2009-09-08 US disclosed
US-20090137584-A1 SULFONYL BENZIMIDAZOLE DERIVATIVES RAQUALIA PHARMA INC. (JP) 2009-05-28 US disclosed
US-20090062460-A1 CURING ACCELERATING COMPOUND-SILICA COMPOSITE MATERIAL, METHOD FOR PRODUCING CURING ACCELERATING COMPOUND-SILICA COMPOSITE MATERIAL, CURING ACCELERATOR, CURABLE RESIN COMPOSITION, AND ELECTRONIC COMPONENT DEVICE HITACHI CHEMICAL CO., LTD. (JP) 2009-03-05 US disclosed
US-20090023855-A1 NOVEL CURABLE RESIN, PRODUCTION METHOD THEREOF, EPOXY RESIN COMPOSITION, AND ELECTRONIC DEVICE RESONAC CORPORATION (JP) 2009-01-22 US disclosed
US-20090012232-A1 Curing accelerator comprising a reaction product of an intramolecular phosphonium salt and a silanol compound; suitable as a material for laminates and adhesives and an electronic parts device comprising an element that has been encapsulated using such a curable resin composition HITACHI CHEMICAL CO., LTD. (JP) 2009-01-08 US disclosed
US-20090005480-A1 REACTION PRODUCT OF PHOSPHINE AND PROTONATED HALOARYL COMPOUND AND USE AS EPOXY CURING ACCELERATOR NAKAMURA SHINYA 2009-01-01 US disclosed
WO-2008153784-A2 HYDROXYBENZYL OR HYDROXYPYRANONEMETHYL ESTERS AS TYROSINASE INHIBITORS EASTMAN CHEMICAL COMPANY (US) 2008-12-18 WO disclosed
EP-1809607-B1 SULFONYL BENZIMIDAZOLE DERIVATIVES PFIZER (US) 2008-12-17 EP disclosed
US-20080306144-A1 Hydroxybenzyl or hydroxypyranonemethyl esters as tyrosinase inhibitors EASTMAN CHEMICAL COMPANY 2008-12-11 US disclosed
WO-2008143777-A1 HYDROQUINONE DERIVATIVE SKIN BRIGHTENING COMPOUNDS EASTMAN CHEMICAL COMPANY (US) 2008-11-27 WO disclosed
EP-1994011-A1 SULFONYL BENZIMIDAZOLE DERIVATIVES Pfizer, Inc. (US) 2008-11-26 EP disclosed
US-20080286219-A1 Hydroquinone derivative skin brightening compounds EASTMAN CHEMICAL COMPANY 2008-11-20 US disclosed
US-20080262135-A1 REACTION PRODUCT OF PHOSPHINE AND PROTONATED HALOARYL COMPOUND AND USE AS EPOXY CURING ACCELERATOR SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-10-23 US disclosed
WO-2007102059-A1 SULFONYL BENZIMIDAZOLE DERIVATIVES PFIZER JAPAN INC. (JP) 2007-09-13 WO disclosed
EP-1809607-A1 SULFONYL BENZIMIDAZOLE DERIVATIVES Pfizer, Inc. (US) 2007-07-25 EP disclosed
WO-2006048754-A1 SULFONYL BENZIMIDAZOLE DERIVATIVES PFIZER JAPAN INC. (JP) 2006-05-11 WO disclosed
US-20060094750-A1 Sulfonyl benzimidazole derivatives KON-I KANA 2006-05-04 US disclosed
US-20050267286-A1 Curing accelerator for curing resin, curing resin composition, electronic component device and method for producing phosphine derivative HITACHI CHEMICAL CO., LTD. (JP) 2005-12-01 US disclosed
EP-1341766-B1 IMIDAZOLONE DERIVATIVES FOR THE TREATMENT OF VIRAL DISEASES HOFFMANN LA ROCHE (CH) 2005-10-26 EP disclosed
US-20050165202-A1 Curing accelerator for curing resin, curing resin composition and electronic component device HITACHI CHEMICAL CO., LTD. (JP) 2005-07-28 US disclosed
EP-0923569-B1 BUTYRIC ACID MATRIX METALLOPROTEINASE INHIBITORS WARNER LAMBERT CO (US) 2004-11-17 EP disclosed
US-6583164-B1 Lyophilized imidazole-1-yl or 1,2,4-triazole-1-yl quaternized with a alklycarbonyloxy alkyl group eliminated in vivo; a saccharide; 4-acetoxymethyl-1-(3-(2-oxo-3-(4-(1H-tetrazol-yl) phenyl)-1-imidazolydinyl)butyl)-1H-1,2,4-triazolium chloride TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2003-06-24 US disclosed
US-6518293-B2 Inhibitors of the human immunodeficiency virus reverse transcriptase enzyme which is involved in viral replication. HOFFMANN-LA ROCHE INC. 2003-02-11 US disclosed
US-20020107272-A1 Anti-HIV imidazolone derivatives F. HOFFMANN-LA ROCHE AG (CH) 2002-08-08 US disclosed
US-6407129-B1 INJECTABLE QUATERNIZED SALT FUNGICIDES; WATER SOLUBILITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-06-18 US disclosed
EP-1120116-A1 ANTIMYCOTIC DRUG COMPOSITION Takeda Chemical Industries, Ltd. (JP) 2001-08-01 EP disclosed
US-6020366-A Butyric acid matrix metalloproteinase inhibitors WARNER-LAMBERT COMPANY (US) 2000-02-01 US disclosed
EP-0973768-A1 AZOLE COMPOUNDS, THEIR PRODUCTION AND THEIR USE Takeda Chemical Industries, Ltd. (JP) 2000-01-26 EP disclosed
EP-0923569-A1 BUTYRIC ACID MATRIX METALLOPROTEINASE INHIBITORS WARNER-LAMBERT COMPANY (US) 1999-06-23 EP disclosed
WO-1998043970-A1 AZOLE COMPOUNDS, THEIR PRODUCTION AND THEIR USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-10-08 WO disclosed
WO-1998006711-A1 BUTYRIC ACID MATRIX METALLOPROTEINASE INHIBITORS WARNER-LAMBERT COMPANY (US) 1998-02-19 WO disclosed
EP-0492178-B1 Naphthoic acid derivative FUJIREBIO KK (JP) 1995-10-04 EP disclosed
US-5324728-A Lipoxygenase inhibiting antiallergens FUJIREBIO INC. (JP) 1994-06-28 US disclosed
EP-0492178-A2 Naphthoic acid derivative FUJIREBIO INC. (JP) 1992-07-01 EP disclosed
EP-0492178-A2 Naphthoic acid derivative FUJIREBIO INC. (JP) 1992-07-01 EP disclosed