SCHEMBL2209971

SCHEMBL2209971

CC(=O)NC(=O)CCCCC(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 1/20 0.54
LMNA P02545 2/20 0.52
TSHR P16473 5/20 0.50
NFKB1 P19838 1/20 0.50
PMP22 Q01453 1/20 0.50
AKR1B1 P15121 1/20 0.48
GPR84 Q9NQS5 7/20 0.46
PPARG P37231 7/20 0.46
PPARD Q03181 7/20 0.46
PPARA Q07869 7/20 0.46
HDAC11 Q96DB2 5/20 0.46
PTPN1 P18031 3/20 0.46
ALDH1A1 P00352 2/20 0.46
TLR2 O60603 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
FABP4 P15090 2/20 0.46
SLC22A6 Q4U2R8 1/20 0.46
SLC22A8 Q8TCC7 1/20 0.46
MEN1 O00255 1/20 0.46
ESR1 P03372 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12967662 0.95 SLC22A6 (0.52) ADRA1ALMNATSHRNFKB1PMP22
SCHEMBL12967673 0.85 PHF8 (0.52) ADRA1ALMNAALDH1A1SLC22A6OR51E2
SCHEMBL12967674 0.82 LMNA (0.48) ADRA1ALMNATSHRNFKB1PMP22
SCHEMBL18746215 0.81 MAPT (0.63) TSHRAKR1B1GPR84PPARGPPARD
SCHEMBL12967379 0.81 MAPT (0.44) ADRA1AGPR84ALDH1A1MEN1KMT2A
SCHEMBL9410605 0.79 HSP90AA1 (0.61) TSHRGPR84PPARGPPARDPPARA
SCHEMBL20724956 0.79 HSP90AA1 (0.61) TSHRGPR84PPARGPPARDPPARA
SCHEMBL5802100 0.79 PAOX (0.54) LMNATSHRNFKB1HDAC11ALDH1A1
SCHEMBL9410595 0.79 HSP90AA1 (0.61) TSHRGPR84PPARGPPARDPPARA
SCHEMBL1573059 0.79 HSP90AA1 (0.61) TSHRGPR84PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8815998-B2 Modified natural rubber, production process for the same and rubber composition and tire prepared by using the same BRIDGESTONE CORPORATION (JP) 2014-08-26 US disclosed
EP-2348055-B1 MODIFIED NATURAL RUBBER AND METHOD FOR PRODUCING MODIFIED NATURAL RUBBER, AND RUBBER COMPOSITION AND TIRE USING THE SAME BRIDGESTONE CORP (JP) 2014-02-12 EP disclosed
WO-2012135669-A1 NITROGEN RING CONTAINING COMPOUNDS FOR TREATMENT OF INFLAMMATORY DISORDERS WEINGARTEN M DAVID (US) 2012-10-04 WO disclosed
US-20110224365-A1 MODIFIED NATURAL RUBBER, PRODUCTION PROCESS FOR THE SAME AND RUBBER COMPOSITION AND TIRE PREPARED BY USING THE SAME BRIDGESTONE CORPORATION (JP) 2011-09-15 US disclosed
EP-2348055-A1 MODIFIED NATURAL RUBBER AND METHOD FOR PRODUCING MODIFIED NATURAL RUBBER, AND RUBBER COMPOSITION AND TIRE USING THE SAME Bridgestone Corporation (JP) 2011-07-27 EP disclosed