SCHEMBL221001

SCHEMBL221001

C=C(C(=O)OCC(CC)CCCC)C(F)(F)F

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.55
CYP3A4 P08684 5/20 0.54
TDP1 Q9NUW8 2/20 0.54
ATM Q13315 1/20 0.54
ALDH1A1 P00352 7/20 0.48
CA2 P00918 4/20 0.48
L3MBTL1 Q9Y468 1/20 0.46
RECQL P46063 1/20 0.46
LMNA P02545 3/20 0.44
MAPK1 P28482 3/20 0.44
HSD17B10 Q99714 1/20 0.43
PRSS1 P07477 1/20 0.43
PRSS2 P07478 1/20 0.43
PRSS3 P35030 1/20 0.43
MMP9 P14780 1/20 0.41
MMP8 P22894 1/20 0.41
MMP14 P50281 1/20 0.41
CA1 P00915 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27941674 0.86 TSHR (0.56) TSHRCYP3A4TDP1ATMALDH1A1
SCHEMBL4998246 0.83 CA1 (0.38) TSHRCYP3A4TDP1ATMCA2
SCHEMBL19056006 0.83 TSHR (0.59) TSHRCYP3A4TDP1ATMALDH1A1
SCHEMBL6657558 0.82 TSHR (0.63) TSHRCYP3A4TDP1ATMALDH1A1
SCHEMBL257295 0.82 CYP3A4 (0.70) TSHRCYP3A4TDP1ATMALDH1A1
SCHEMBL16772 0.81 TSHR (0.61) TSHRCYP3A4TDP1ATMALDH1A1
SCHEMBL14577150 0.81 CYP3A4 (0.60) TSHRCYP3A4TDP1ATMALDH1A1
SCHEMBL1269088 0.81 TSHR (0.61) TSHRCYP3A4TDP1ATMALDH1A1
Charcoal, Activated SCHEMBL11214727 0.80 TSHR (0.59) TSHRCYP3A4TDP1ATMALDH1A1
SCHEMBL16412767 0.80 TSHR (0.59) TSHRCYP3A4TDP1ATMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4613657-A APROTIC SOLVENT ALKALI METAL ALKOXIDE, OPTICS, PAINTS, RESISTS CENTRAL GLASS COMPANY, LIMITED (JP) 1986-09-23 US claimed
US-9733564-B2 Copolymers for lithography and method for producing same, resist composition, method for producing substrate with pattern formed thereupon, method for evaluating copolymers, and method for analyzing copolymer compositions MITSUBISHI CHEMICAL CORPORATION (JP) 2017-08-15 US disclosed
US-9188857-B2 Resist polymer, process for production thereof, resist composition, and process for production of substrates with patterns thereon MITSUBISHI RAYON CO., LTD. (JP) 2015-11-17 US disclosed
US-8614283-B2 Resist polymer, resist composition, process for pattern formation, and starting compounds for production of the resist polymer MITSUBISHI RAYON CO., LTD. (JP) 2013-12-24 US disclosed
US-8580481-B2 Resist polymer and resist composition MITSUBISHI RAYON CO., LTD. (JP) 2013-11-12 US disclosed
US-20130252181-A1 RESIST POLYMER, PROCESS FOR PRODUCTION THEREOF, RESIST COMPOSITION, AND PROCESS FOR PRODUCTION OF SUBSTRATES WITH PATTERNS THEREON MITSUBISHI RAYON CO., LTD. (JP) 2013-09-26 US disclosed
US-20130224654-A1 COPOLYMERS FOR LITHOGRAPHY AND METHOD FOR PRODUCING SAME, RESIST COMPOSITION, METHOD FOR PRODUCING SUBSTRATE WITH PATTERN FORMED THEREUPON, METHOD FOR EVALUATING COPOLYMERS, AND METHOD FOR ANALYZING COPOLYMER COMPOSITIONS MITSUBISHI RAYON CO., LTD. (JP) 2013-08-29 US disclosed
US-8476401-B2 Resist polymer, process for production thereof, resist composition, and process for production of substrated with patterns thereon MITSUBISHI RAYON CO., LTD. (JP) 2013-07-02 US disclosed
US-20120315459-A1 CARBON NANOTUBE SHEET AND PROCESS FOR PRODUCTION THEREOF TAIYO NIPPON SANSO CORPORATION (JP) 2012-12-13 US disclosed
US-8241829-B2 Resist polymer, resist composition, process for pattern formation, and starting compounds for production of the resist polymer MITSUBISHI RAYON CO., LTD. (JP) 2012-08-14 US disclosed
US-20090263743-A1 RESIST POLYMER AND RESIST COMPOSITION MITSUBISHI RAYON CO., LTD. (JP) 2009-10-22 US disclosed
US-20090226851-A1 (METH)ACRYLATE, POLYMER AND RESIST COMPOSITION MITSUBISHI RAYON CO., LTD. (JP) 2009-09-10 US disclosed
US-7575846-B2 Resist polymer and resist composition MITSUBISHI RAYON CO., LTD. (JP) 2009-08-18 US disclosed
US-20090198065-A1 RESIST POLYMER, RESIST COMPOSITION, PROCESS FOR PATTERN FORMATION, AND STARTING COMPOUNDS FOR PRODUCTION OF THE RESIST POLYMER MITSUBISHI RAYON CO., LTD. (JP) 2009-08-06 US disclosed
US-20080032241-A1 Resist Polymer, Process For Production Thereof, Resist Composition, And Process For Production Of Substrated With Patterns Thereon MITSUBISHI RAYON CO., LTD. (JP) 2008-02-07 US disclosed
US-20080003529-A1 (Meth)Acrylate, Polymer and Resist Composition MITSUBISHI RAYON CO., LTD. (JP) 2008-01-03 US disclosed
US-20070190449-A1 Resist polymer, resist composition, process for pattern formation, and starting compounds for production of the resist polymer MITSUBISHI RAYON CO., LTD. (JP) 2007-08-16 US disclosed
US-20060127801-A1 Resist polymer and resist composition MITSUBISHI RAYON CO., LTD. (JP) 2006-06-15 US disclosed
US-4613657-A APROTIC SOLVENT ALKALI METAL ALKOXIDE, OPTICS, PAINTS, RESISTS CENTRAL GLASS COMPANY, LIMITED (JP) 1986-09-23 US disclosed
US-4609715-A RADICALLY POLYMERIZED CENTRAL GLASS COMPANY, LIMITED (JP) 1986-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090198065-A1 RESIST POLYMER, RESIST COMPOSITION, PROCESS FOR PATTERN FORMATION, AND STARTING COMPOUNDS FOR PRODUCTION OF THE RESIST POLYMER CHRM1, CHRM2, PKN2 TSHR 1359/4885CYP3A4 1751/4885TDP1 2115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.