Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.98 |
| ▸ | PPARG | P37231 | 13/20 | 0.98 |
| ▸ | PPARD | Q03181 | 6/20 | 0.98 |
| ▸ | GMNN | O75496 | 1/20 | 0.98 |
| ▸ | USP2 | O75604 | 1/20 | 0.98 |
| ▸ | USP1 | O94782 | 1/20 | 0.98 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.98 |
| ▸ | LMNA | P02545 | 1/20 | 0.98 |
| ▸ | TP53 | P04637 | 1/20 | 0.98 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.98 |
| ▸ | POLB | P06746 | 1/20 | 0.98 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.98 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.98 |
| ▸ | MAPT | P10636 | 1/20 | 0.98 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.98 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.98 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.98 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.98 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.98 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.98 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gw7647 SCHEMBL361372 | 0.99 | PPARA (1.00) | PPARAPPARGPPARDGMNNUSP2 | |
| SCHEMBL6552622 | 0.88 | PPARA (0.80) | PPARAPPARGPPARDGMNNUSP2 | |
| SCHEMBL4265257 | 0.86 | PPARA (1.00) | PPARAPPARGPPARDGMNNUSP2 | |
| SCHEMBL16147204 | 0.83 | PPARA (1.00) | PPARAPPARGPPARDGMNNUSP2 | |
| SCHEMBL6552333 | 0.82 | PPARA (0.73) | PPARAPPARGPPARDGMNNUSP2 | |
| SCHEMBL16147851 | 0.81 | PPARA (1.00) | PPARAPPARGPPARDGMNNUSP2 | |
| SCHEMBL16147225 | 0.80 | PPARA (1.00) | PPARAPPARGPPARDGMNNUSP2 | |
| SCHEMBL12274271 | 0.79 | PPARA (0.67) | PPARAPPARGPPARDGMNNUSP2 | |
| SCHEMBL21123888 | 0.79 | PPARA (0.67) | PPARAPPARGPPARDGMNNUSP2 | |
| SCHEMBL3675079 | 0.78 | PPARA (0.65) | PPARAPPARGPPARDGMNNUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11420934-B2 | PPAR agonists | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2022-08-23 | — | — | US | disclosed |
| US-20200190019-A1 | PPAR AGONISTS | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11420934-B2 | PPAR agonists | PPARG, PPARD, PPARA | PPARA 3/4885PPARG 1/4885PPARD 2/4885 |
| US-20200190019-A1 | PPAR AGONISTS | PPARG, PPARD, PPARA | PPARA 3/4885PPARG 1/4885PPARD 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.