Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 13/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20250760 | 0.93 | TRPM8 (0.71) | TRPM8ALDH1A1SMN1; SMN2HTR2AHTR2C | |
| SCHEMBL1699151 | 0.91 | TRPM8 (1.00) | TRPM8ALDH1A1SMN1; SMN2LMNAHTR2A | |
| SCHEMBL1699149 | 0.91 | TRPM8 (1.00) | TRPM8ALDH1A1SMN1; SMN2LMNAHTR2A | |
| SCHEMBL10270947 | 0.86 | TRPM8 (1.00) | TRPM8ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL20777249 | 0.83 | TRPM8 (0.57) | TRPM8ALDH1A1SMN1; SMN2LMNAHTR2A | |
| SCHEMBL22074394 | 0.83 | TRPM8 (0.57) | TRPM8ALDH1A1SMN1; SMN2LMNAHTR2A | |
| SCHEMBL30579664 | 0.83 | TRPM8 (0.57) | TRPM8ALDH1A1SMN1; SMN2LMNAHTR2A | |
| SCHEMBL20773809 | 0.83 | TRPM8 (0.62) | TRPM8ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL10270350 | 0.82 | TRPM8 (0.74) | TRPM8ALDH1A1SMN1; SMN2LMNAHTR2A | |
| SCHEMBL13277324 | 0.82 | TRPM8 (1.00) | TRPM8ALDH1A1SMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2501761-B1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | SYMRISE AG (DE) | 2020-06-17 | — | — | EP | disclosed |