Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 10/20 | 0.77 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22100834 | 0.88 | TRPM8 (0.76) | TRPM8HTTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL22100807 | 0.88 | TRPM8 (0.74) | TRPM8HTTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL13277736 | 0.87 | TRPM8 (1.00) | TRPM8HTTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10271033 | 0.87 | TRPM8 (1.00) | TRPM8HTTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL22100812 | 0.81 | TRPM8 (0.76) | TRPM8HTTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL22100829 | 0.81 | TRPM8 (0.60) | TRPM8HTTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL22100766 | 0.75 | TRPM8 (0.55) | TRPM8HTTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL13277324 | 0.75 | TRPM8 (1.00) | TRPM8HTTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30532215 | 0.75 | TRPM8 (1.00) | TRPM8HTTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10270359 | 0.75 | TRPM8 (1.00) | TRPM8HTTALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2501761-B1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | SYMRISE AG (DE) | 2020-06-17 | — | — | EP | disclosed |