Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 12/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10575004 | 0.86 | TRPM8 (0.69) | TRPM8ALDH1A1SMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL10271035 | 0.84 | TRPM8 (1.00) | TRPM8ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL1699151 | 0.83 | TRPM8 (1.00) | TRPM8ALDH1A1SMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL1699149 | 0.83 | TRPM8 (1.00) | TRPM8ALDH1A1SMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL1151509 | 0.81 | ESR1 (0.64) | TRPM8 | |
| SCHEMBL1151508 | 0.81 | ESR1 (0.64) | TRPM8 | |
| SCHEMBL13277569 | 0.81 | TRPM8 (1.00) | TRPM8ALDH1A1SMN1; SMN2 | |
| SCHEMBL10270778 | 0.81 | TRPM8 (1.00) | TRPM8ALDH1A1SMN1; SMN2 | |
| SCHEMBL10270353 | 0.79 | TRPM8 (0.66) | TRPM8ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL10270345 | 0.77 | TRPM8 (1.00) | TRPM8ALDH1A1SMN1; SMN2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2501761-B1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | SYMRISE AG (DE) | 2020-06-17 | — | — | EP | disclosed |