Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.41 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2844280 | 1.00 | ANPEP (0.42) | ANPEPBTKTSHRSLC6A1SLC6A11 | |
| SCHEMBL3939408 | 1.00 | ANPEP (0.42) | ANPEPBTKTSHRSLC6A1SLC6A11 | |
| SCHEMBL2183635 | 1.00 | ANPEP (0.42) | ANPEPBTKTSHRSLC6A1SLC6A11 | |
| SCHEMBL4748647 | 1.00 | ANPEP (0.42) | ANPEPBTKTSHRSLC6A1SLC6A11 | |
| SCHEMBL404285 | 1.00 | ANPEP (0.42) | ANPEPBTKTSHRSLC6A1SLC6A11 | |
| SCHEMBL3670041 | 1.00 | ANPEP (0.42) | ANPEPBTKTSHRSLC6A1SLC6A11 | |
| SCHEMBL5432415 | 1.00 | ANPEP (0.42) | ANPEPBTKTSHRSLC6A1SLC6A11 | |
| SCHEMBL5428215 | 0.98 | ANPEP (0.41) | ANPEPBTKTSHRSLC6A1SLC6A11 | |
| Cesium SCHEMBL5428219 | 0.98 | ANPEP (0.41) | ANPEPBTKTSHRSLC6A1SLC6A11 | |
| SCHEMBL9729349 | 0.95 | TSHR (0.43) | ANPEPBTKTSHRSLC6A1SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-112041316-A | Isoxazole O-linked carbamoylcyclohexanoic acids as LPA antagonists | 百时美施贵宝公司 | 2020-12-04 | — | — | CN | disclosed |
| EP-3738954-A1 | METHOD OF PREPARATION OF SUBSTITUTED 2,4-DIAMINO-PYRIMIDINE-5-CARBOXAMIDES | Signal Pharmaceuticals, LLC (US) | 2020-11-18 | — | — | EP | disclosed |
| EP-3728210-A1 | ISOXAZOLE N-LINKED CARBAMOYL CYCLOHEXYL ACIDS AS LPA ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2020-10-28 | — | — | EP | disclosed |
| EP-3099302-B1 | CRYSTALLINE FORMS OF 2-(TERT-BUTYLAMINO)-4-((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYLAMINO)-PYRIMIDINE-5-CARBOXAMIDE | SIGNAL PHARM LLC (US) | 2020-06-17 | — | — | EP | disclosed |