Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.41 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18811762 | 0.98 | CES2 (0.46) | TSHRCES2CES1SLC6A1SLC6A11 | |
| SCHEMBL5432415 | 0.95 | ANPEP (0.42) | TSHRCES2CES1SLC6A1SLC6A11 | |
| SCHEMBL3670041 | 0.95 | ANPEP (0.42) | TSHRCES2CES1SLC6A1SLC6A11 | |
| SCHEMBL3939408 | 0.95 | ANPEP (0.42) | TSHRCES2CES1SLC6A1SLC6A11 | |
| SCHEMBL4748647 | 0.95 | ANPEP (0.42) | TSHRCES2CES1SLC6A1SLC6A11 | |
| SCHEMBL404285 | 0.95 | ANPEP (0.42) | TSHRCES2CES1SLC6A1SLC6A11 | |
| SCHEMBL2183635 | 0.95 | ANPEP (0.42) | TSHRCES2CES1SLC6A1SLC6A11 | |
| SCHEMBL2844280 | 0.95 | ANPEP (0.42) | TSHRCES2CES1SLC6A1SLC6A11 | |
| SCHEMBL22100987 | 0.95 | ANPEP (0.42) | TSHRCES2CES1SLC6A1SLC6A11 | |
| Cesium SCHEMBL5428219 | 0.93 | ANPEP (0.41) | TSHRCES2CES1SLC6A1SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175290-A | Bronchodilator, cardiotonic agents | MARION MERRELL DOW INC. (US) | 1992-12-29 | — | — | US | disclosed |