Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CPS1 | P31327 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21400899 | 0.95 | KDM4E (0.42) | PRKCZKDM4EATMKMT2APTGS1 | |
| SCHEMBL27421754 | 0.90 | KDM4E (0.38) | PRKCZKDM4EATMKMT2APTGS1 | |
| SCHEMBL22101130 | 0.89 | ERN1 (0.43) | PRKCZADORA3DHODHCPS1ERN1 | |
| SCHEMBL25908254 | 0.88 | KDM4E (0.36) | PRKCZKDM4EERN1ATMKMT2A | |
| SCHEMBL22592232 | 0.88 | ELANE (0.41) | PRKCZKDM4EATMKMT2APTGS1 | |
| SCHEMBL25935937 | 0.88 | ELANE (0.41) | PRKCZKDM4EATMKMT2APTGS1 | |
| SCHEMBL12196853 | 0.88 | GRM2 (0.44) | PRKCZCPS1ERN1GRM2PRKAB2 | |
| SCHEMBL21400896 | 0.86 | ELANE (0.41) | PRKCZADORA3DHODHERN1GRM2 | |
| SCHEMBL11053851 | 0.84 | BACE1 (0.48) | MTNR1AMTNR1BADORA3KDM4EATM | |
| SCHEMBL25944850 | 0.84 | ERN1 (0.39) | PRKCZADORA3DHODHERN1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3944011-A1 | LIQUID-CRYSTAL DISPLAY | Merck Patent GmbH (DE) | 2022-01-26 | — | — | EP | disclosed |
| EP-3848436-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2021-07-14 | — | — | EP | disclosed |
| EP-3730591-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2020-10-28 | — | — | EP | disclosed |
| EP-3666853-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2020-06-17 | — | — | EP | disclosed |