SCHEMBL12196853

SCHEMBL12196853

C=C(C)C(=O)Oc1ccc(-c2ccc(OC)cc2F)c(F)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 1/20 0.44
ELANE P08246 1/20 0.44
PRKAB2 O43741 2/20 0.43
PRKAG1 P54619 2/20 0.43
PRKAA2 P54646 2/20 0.43
PRKAA1 Q13131 2/20 0.43
PRKAG3 Q9UGI9 2/20 0.43
PRKAG2 Q9UGJ0 2/20 0.43
PRKAB1 Q9Y478 2/20 0.43
PRKCZ Q05513 1/20 0.43
MAPT P10636 1/20 0.42
CPS1 P31327 4/20 0.42
ERN1 O75460 1/20 0.42
GPR35 Q9HC97 1/20 0.42
KMT2A Q03164 1/20 0.41
ATM Q13315 1/20 0.41
APP P05067 1/20 0.41
CYP2C19 P33261 1/20 0.41
AMY1A P0DUB6 2/20 0.40
BACE1 P56817 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9607783 0.94 ELANE (0.49) GRM2ELANEPRKAB2PRKAG1PRKAA2
SCHEMBL22101130 0.93 ERN1 (0.43) GRM2ELANEPRKAB2PRKAG1PRKAA2
SCHEMBL12196852 0.90 CYP2C19 (0.50) GRM2ELANEPRKAB2PRKAG1PRKAA2
SCHEMBL21400896 0.90 ELANE (0.41) GRM2ELANEPRKAB2PRKAG1PRKAA2
SCHEMBL20311934 0.90 CYP2C19 (0.53) ELANEPRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL18869114 0.89 CYP2C19 (0.52) ELANEPRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL23072778 0.89 PRKCZ (0.39) GRM2ELANEPRKAB2PRKAG1PRKAA2
SCHEMBL25944850 0.88 ERN1 (0.39) GRM2ELANEPRKAB2PRKAG1PRKAA2
SCHEMBL22101129 0.88 PRKCZ (0.43) GRM2PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL18699651 0.88 GRM2 (0.43) GRM2ELANEPRKAB2PRKAG1PRKAA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4306614-A1 LIQUID-CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2024-01-17 EP disclosed
EP-3551723-B1 ADDITIVES FOR LIQUID CRYSTAL MIXTURES MERCK PATENT GMBH (DE) 2023-09-20 EP disclosed
EP-3944011-A1 LIQUID-CRYSTAL DISPLAY Merck Patent GmbH (DE) 2022-01-26 EP disclosed
EP-3257916-B1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2021-11-17 EP disclosed
EP-3848436-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2021-07-14 EP disclosed
EP-3688118-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2021-05-19 EP disclosed
EP-3521401-B1 COMPOUNDS FOR HOMEOTROPIC ALIGNMENT OF LIQUID CRYSTALINE MEDIA MERCK PATENT GMBH (DE) 2021-04-21 EP disclosed
EP-3587536-B1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2021-03-24 EP disclosed
EP-3757192-A1 LIQUID CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2020-12-30 EP disclosed
EP-3127989-B1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2020-12-23 EP disclosed
US-20160259212-A1 LIQUID CRYSTAL DISPLAY AND MANUFACTURING METHOD THEREOF SAMSUNG DISPLAY CO., LTD. (KR) 2016-09-08 US disclosed
US-9081237-B2 Pixel electrode panel, a liquid crystal display panel assembly and methods for manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-07-14 US disclosed
US-9057917-B2 Pixel electrode panel, a liquid crystal display panel assembly and methods for manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-16 US disclosed
US-20150163968-A1 LIQUID CRYSTAL DISPLAY DEVICE, ALIGNMENT FILM, AND METHODS FOR MANUFACTURING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2015-06-11 US disclosed
US-8962106-B2 Liquid crystal display device, alignment film, and methods for manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-02-24 US disclosed
US-8865274-B2 Liquid crystal display device, alignment film, and methods for manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2014-10-21 US disclosed
EP-2520972-A2 Liquid crystal display device alignment film, and method for manufacturing the same Samsung Display Co., Ltd. (KR) 2012-11-07 EP disclosed
US-20120249940-A1 LIQUID CRYSTAL DISPLAY DEVICE, ALIGNMENT FILM, AND METHODS FOR MANUFACTURING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-10-04 US disclosed
US-20110242468-A1 PIXEL ELECTRODE PANEL, A LIQUID CRYSTAL DISPLAY PANEL ASSEMBLY AND METHODS FOR MANUFACTURING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-10-06 US disclosed
US-20110242443-A1 PIXEL ELECTRODE PANEL, A LIQUID CRYSTAL DISPLAY PANEL ASSEMBLY AND METHODS FOR MANUFACTURING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-10-06 US disclosed