Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FADS1 | O60427 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22101182 | 0.81 | SMN1; SMN2 (0.44) | KDM4EGLAGAASMN1; SMN2NPSR1 | |
| SCHEMBL22393760 | 0.81 | MAP3K5 (0.35) | KDM4EGLAGAARXFP1MAPT | |
| SCHEMBL22101724 | 0.78 | KDM4E (0.45) | KDM4EGLAGAASMN1; SMN2NPSR1 | |
| SCHEMBL11362099 | 0.78 | KDM4E (0.49) | KDM4EGLAGAASMN1; SMN2NPSR1 | |
| SCHEMBL18642162 | 0.77 | RAB9A (0.52) | KDM4EGLAGAASMN1; SMN2NPSR1 | |
| SCHEMBL21772471 | 0.76 | SMN1; SMN2 (0.42) | KDM4EGLAGAASMN1; SMN2NPSR1 | |
| SCHEMBL22101906 | 0.76 | KDM4E (0.43) | KDM4EGLAGAASMN1; SMN2NPSR1 | |
| SCHEMBL22279584 | 0.74 | RAB9A (0.65) | KDM4EGLAGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL22101368 | 0.74 | MAPT (0.33) | KDM4EGLAGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL19775028 | 0.73 | NR1H4 (0.49) | KDM4EGAASMN1; SMN2NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666772-A1 | DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-06-17 | — | — | EP | disclosed |