SCHEMBL2210132

SCHEMBL2210132

C(=C(c1ccccc1)c1ccc(N(c2ccccc2)c2ccccc2)cc1)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.60
CYP19A1 P11511 3/20 0.53
CYP11B2 P19099 2/20 0.53
CYP2D6 P10635 2/20 0.49
PTGS2 P35354 5/20 0.46
ESR2 Q92731 2/20 0.45
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
MAPT P10636 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
AKR1C1 Q04828 1/20 0.41
HPGD P15428 1/20 0.40
PSMB1 P20618 1/20 0.39
PSMB5 P28074 1/20 0.39
PSMB2 P49721 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23316166 1.00 ESR1 (0.60) ESR1CYP19A1CYP11B2CYP2D6PTGS2
SCHEMBL8633334 1.00 ESR1 (0.60) ESR1CYP19A1CYP11B2CYP2D6PTGS2
SCHEMBL14928221 1.00 ESR1 (0.60) ESR1CYP19A1CYP11B2CYP2D6PTGS2
SCHEMBL4252025 1.00 ESR1 (0.60) ESR1CYP19A1CYP11B2CYP2D6PTGS2
SCHEMBL21387912 1.00 ESR1 (0.60) ESR1CYP19A1CYP11B2CYP2D6PTGS2
SCHEMBL4310935 0.96 ESR1 (0.55) ESR1CYP19A1CYP11B2CYP2D6PTGS2
SCHEMBL14044715 0.96 ESR1 (0.55) ESR1CYP19A1CYP11B2CYP2D6PTGS2
SCHEMBL4310932 0.96 ESR1 (0.55) ESR1CYP19A1CYP11B2CYP2D6PTGS2
SCHEMBL14018371 0.96 ESR1 (0.55) ESR1CYP19A1CYP11B2CYP2D6PTGS2
SCHEMBL4077708 0.96 ESR1 (0.59) ESR1CYP19A1CYP11B2CYP2D6PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5192633-A Ionization potential MITA INDUSTRIAL CO., LTD. (JP) 1993-03-09 US claimed
JP-10097087-A None JP disclosed
JP-11084692-A None JP disclosed
CN-103242167-B Amine compound, photoelectric conductor for electronic photography, image forming method, image forming apparatus and handle box RICOH CO., LTD. (JP) 2016-02-24 CN disclosed
US-8679711-B2 Electrophotographic photoreceptor KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2014-03-25 US disclosed
CN-103242167-A Amine compound, electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge RICOH CO LTD 2013-08-14 CN disclosed
US-8481233-B2 Organic photoreceptor, image forming apparatus and process cartridge KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2013-07-09 US disclosed
US-8380109-B2 Image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2013-02-19 US disclosed
US-8182970-B2 Image forming method KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-05-22 US disclosed
US-8177604-B2 Surface abrading method of photosensitive layer of electrophotographic photoreceptor KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-05-15 US disclosed
US-4935322-A Photosensitive member comprising a bisazo compound MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1990-06-19 US disclosed
US-4931371-A On electroconductive support CANON KABUSHIKI KAISHA (JP) 1990-06-05 US disclosed
US-4895782-A HEATING THE DISAZO PIGMENT IN A KETONE SOLVENT AS A DISPERSION PRETREATMENT; PHOTOSENSITIVITY; STABILITY CANON KABUSHIKI KAISHA (JP) 1990-01-23 US disclosed
US-4895781-A BENZANTHRONE OR DICYANOMETHYLIDENE BENZ(DE)ANTHRACENE DERIVATIVES COUPLED TO A PHENOLIC RESIDUE; PHOTOSENSITIVITY; DURABILITY; LASER PRINTING CANON KABUSHIKI KAISHA (JP) 1990-01-23 US disclosed
US-4894304-A PHOTOCONDUCTORS, MULTILAYER MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1990-01-16 US disclosed
US-4888261-A WITH AZO PIGMENT AS CHARGE GENERATING COMPOUND CANON KABUSHIKI KAISHA (JP) 1989-12-19 US disclosed
US-4882427-A Titanium phthalocyanine optical semiconductor material and electrophotographic plate using same TOYO INK MANUFACTURING CO., LTD. (JP) 1989-11-21 US disclosed
US-4865934-A CHARGE GENERATING AND TRANSPORT LAYERS, POLYVINYL BUTYRAL, PHTHALOCYANINE, HYDRAZONE, DYE MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1989-09-12 US disclosed
US-4865935-A CHARGE GENERATING, CHARGE TRANSFER, ELECTROGRAPHY MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1989-09-12 US disclosed
US-4810608-A CHARGE GENERATION AGENTS MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1989-03-07 US disclosed