Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23316166 | 1.00 | ESR1 (0.60) | ESR1CYP19A1CYP11B2CYP2D6PTGS2 | |
| SCHEMBL8633334 | 1.00 | ESR1 (0.60) | ESR1CYP19A1CYP11B2CYP2D6PTGS2 | |
| SCHEMBL2210132 | 1.00 | ESR1 (0.60) | ESR1CYP19A1CYP11B2CYP2D6PTGS2 | |
| SCHEMBL4252025 | 1.00 | ESR1 (0.60) | ESR1CYP19A1CYP11B2CYP2D6PTGS2 | |
| SCHEMBL21387912 | 1.00 | ESR1 (0.60) | ESR1CYP19A1CYP11B2CYP2D6PTGS2 | |
| SCHEMBL4310935 | 0.96 | ESR1 (0.55) | ESR1CYP19A1CYP11B2CYP2D6PTGS2 | |
| SCHEMBL14044715 | 0.96 | ESR1 (0.55) | ESR1CYP19A1CYP11B2CYP2D6PTGS2 | |
| SCHEMBL4310932 | 0.96 | ESR1 (0.55) | ESR1CYP19A1CYP11B2CYP2D6PTGS2 | |
| SCHEMBL14018371 | 0.96 | ESR1 (0.55) | ESR1CYP19A1CYP11B2CYP2D6PTGS2 | |
| SCHEMBL4077708 | 0.96 | ESR1 (0.59) | ESR1CYP19A1CYP11B2CYP2D6PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8828559-B2 | Heterocyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2014-09-09 | — | — | US | disclosed |
| US-8828559-B2 | Heterocyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2014-09-09 | — | — | US | disclosed |
| US-20130113367-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG MOBILE DISPLAY CO., LTD. (KR) | 2013-05-09 | — | — | US | disclosed |
| US-20130113367-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG MOBILE DISPLAY CO., LTD. (KR) | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130113367-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | TELO2, ARL1, CRY1 | ESR1 52/4885CYP19A1 45/4885CYP11B2 561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.