Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22101372 | 0.89 | HDAC1 (0.35) | HDAC1KDM4EGLAGAA | |
| SCHEMBL22101810 | 0.85 | HDAC1 (0.34) | HDAC1KDM4EGLAGAA | |
| SCHEMBL22101373 | 0.85 | KDM4E (0.38) | HDAC1KDM4EGLAGAA | |
| SCHEMBL22101368 | 0.78 | MAPT (0.33) | HDAC1KDM4EGLAGAA | |
| SCHEMBL22101371 | 0.77 | RXFP1 (0.35) | HDAC1KDM4EGLAGAA | |
| SCHEMBL22101410 | 0.71 | — | — | |
| SCHEMBL22101363 | 0.70 | TP53 (0.42) | KDM4EGAA | |
| SCHEMBL22393705 | 0.69 | HDAC1 (0.35) | HDAC1KDM4EGLAGAA | |
| SCHEMBL22101456 | 0.69 | MAPT (0.37) | KDM4E | |
| SCHEMBL22101906 | 0.68 | KDM4E (0.43) | HDAC1KDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666772-A1 | DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-06-17 | — | — | EP | disclosed |