Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22101363 | 0.84 | TP53 (0.42) | MAPTTP53LMNAPOLBKDM4E | |
| SCHEMBL22101383 | 0.81 | PIK3CB (0.30) | — | |
| SCHEMBL22101264 | 0.78 | ADORA3 (0.37) | MAPT | |
| SCHEMBL22101372 | 0.76 | HDAC1 (0.35) | MAPTTP53KDM4ERXFP1SMN1; SMN2 | |
| SCHEMBL22101810 | 0.74 | HDAC1 (0.34) | MAPTTP53KDM4ERXFP1ALDH1A1 | |
| SCHEMBL22101340 | 0.73 | TP53 (0.41) | MAPTTP53LMNAPOLBKDM4E | |
| SCHEMBL22101452 | 0.71 | MAPT (0.33) | MAPT | |
| SCHEMBL22101459 | 0.71 | FFAR4 (0.32) | — | |
| SCHEMBL22101373 | 0.70 | KDM4E (0.38) | MAPTTP53LMNAKDM4ERXFP1 | |
| SCHEMBL22101491 | 0.69 | ALDH1A1 (0.33) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666772-A1 | DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-06-17 | — | — | EP | disclosed |