Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | CCNC | P24863 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11404207 | 0.92 | KMT2A (0.50) | KMT2AELANELMNATP53HTT | |
| SCHEMBL12444455 | 0.88 | KMT2A (0.54) | KMT2AELANELMNATP53HTT | |
| SCHEMBL26365445 | 0.86 | ELANE (0.52) | KMT2AELANEHTTSMN1; SMN2TDP1 | |
| SCHEMBL17666399 | 0.86 | ELANE (0.49) | KMT2AELANELMNAHTTSMN1; SMN2 | |
| SCHEMBL26240064 | 0.86 | ELANE (0.49) | KMT2AELANEHTTSMN1; SMN2TDP1 | |
| SCHEMBL22102176 | 0.85 | NPC1 (0.45) | KMT2AELANELMNAHTTSMN1; SMN2 | |
| SCHEMBL19577866 | 0.85 | KMT2A (0.52) | KMT2ACCNCCDK8ELANELMNA | |
| SCHEMBL25500917 | 0.83 | ELANE (0.51) | KMT2AELANEHTTSMN1; SMN2TDP1 | |
| SCHEMBL26186181 | 0.83 | RAB9A (0.53) | KMT2AELANELMNAHTTSMN1; SMN2 | |
| SCHEMBL25500845 | 0.83 | KMT2A (0.61) | KMT2AELANEHTTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230383187-A1 | Mesogen Compounds | TRANSITIONS OPTICAL, LTD. (IE) | 2023-11-30 | — | — | US | disclosed |
| US-11773326-B2 | Mesogen compounds | TRANSITIONS OPTICAL, LTD. (IE) | 2023-10-03 | — | — | US | disclosed |
| WO-2020120282-A1 | MESOGEN COMPOUNDS | TRANSITIONS OPTICAL, LTD. (IE) | 2020-06-18 | — | — | WO | disclosed |