Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.34 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11352700 | 0.81 | NOTUM (0.37) | OPRM1OPRL1MAP3K14CYP11B1CYP11B2 | |
| SCHEMBL9274574 | 0.81 | CYP11B1 (0.38) | MAP3K14CYP11B1CYP11B2NR3C2CYP19A1 | |
| SCHEMBL22102579 | 0.78 | MAP3K14 (0.34) | OPRM1OPRL1MAP3K14CYP11B1CYP11B2 | |
| SCHEMBL22103239 | 0.78 | MAP3K14 (0.34) | OPRM1OPRL1MAP3K14CYP11B1CYP11B2 | |
| SCHEMBL15287132 | 0.78 | MAP3K14 (0.34) | OPRM1OPRL1MAP3K14CYP11B1CYP11B2 | |
| SCHEMBL23792923 | 0.78 | UGT2B17 (0.40) | OPRM1OPRL1MAP3K14CYP11B1CYP11B2 | |
| SCHEMBL22102913 | 0.78 | OPRL1 (0.37) | OPRM1OPRL1MAP3K14CYP11B1CYP11B2 | |
| SCHEMBL16798270 | 0.78 | KDM1A (0.41) | CYP11B1CYP11B2NR3C2CYP19A1POLL | |
| SCHEMBL18094370 | 0.78 | KDM1A (0.41) | CYP11B1CYP11B2NR3C2CYP19A1POLL | |
| SCHEMBL9282806 | 0.78 | HTR2A (0.40) | MAP3K14CYP11B1CYP11B2NR3C2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522596-A1 | DIHYDROINDENE DERIVATIVES AS MALT1 INHIBITORS | C4X Discovery Limited (GB) | 2025-03-19 | — | — | EP | disclosed |
| CN-119497712-A | Indane derivatives as MALT1 inhibitors | 希四克斯探索有限公司 | 2025-02-21 | — | — | CN | disclosed |
| WO-2023218203-A1 | DIHYDROINDENE DERIVATIVES AS MALT1 INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |
| WO-2020119592-A1 | NOVEL THREE-RING FUSED STRUCTURE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 信达生物制药(苏州)有限公司 | 2020-06-18 | — | — | WO | disclosed |