SCHEMBL22103239 — predicted protein targets

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	MAP3K14	Q99558	1/20	0.34

▸	OPRM1	P35372	2/20	0.32

▸	OPRL1	P41146	2/20	0.32

▸	CYP11B1	P15538	2/20	0.31

▸	CYP11B2	P19099	2/20	0.31

▸	POLL	Q9UGP5	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL11352700	0.81	NOTUM (0.37)	MAP3K14OPRM1OPRL1CYP11B1CYP11B2
SCHEMBL22102913	0.78	OPRL1 (0.37)	MAP3K14OPRM1OPRL1CYP11B1CYP11B2
SCHEMBL29660414	0.78	MAP3K14 (0.34)	MAP3K14OPRM1OPRL1CYP11B1CYP11B2
SCHEMBL22102579	0.78	MAP3K14 (0.34)	MAP3K14OPRM1OPRL1CYP11B1CYP11B2
SCHEMBL15287132	0.78	MAP3K14 (0.34)	MAP3K14OPRM1OPRL1CYP11B1CYP11B2
SCHEMBL22102575	0.78	OPRM1 (0.34)	MAP3K14OPRM1OPRL1CYP11B1CYP11B2
SCHEMBL11110438	0.77	HTR2C (0.45)	MAP3K14OPRM1OPRL1POLL
SCHEMBL1508419	0.77	HTR2C (0.45)	MAP3K14OPRM1OPRL1POLL
SCHEMBL1508379	0.77	HTR2C (0.45)	MAP3K14OPRM1OPRL1POLL
SCHEMBL30748004	0.74	NOTUM (0.41)	MAP3K14OPRM1OPRL1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2020119592-A1	NOVEL THREE-RING FUSED STRUCTURE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF	信达生物制药(苏州)有限公司	2020-06-18	—	—	WO	disclosed