Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661309 | 0.90 | KDM4E (0.48) | KDM4E | |
| SCHEMBL28022825 | 0.87 | IAPP (0.47) | KDM4EPOLB | |
| SCHEMBL30873948 | 0.81 | NPSR1 (0.57) | NPSR1FFAR1FFAR4PTGER1PTGER4 | |
| SCHEMBL1450886 | 0.81 | NPSR1 (0.57) | NPSR1FFAR1FFAR4PTGER1PTGER4 | |
| SCHEMBL11069661 | 0.81 | AKR1B1 (0.57) | AKR1B1 | |
| SCHEMBL4699564 | 0.81 | TAAR1 (0.55) | NPSR1FFAR1PTGER1PTGER4PTGER3 | |
| Ethane SCHEMBL10497410 | 0.81 | FFAR1 (0.56) | NPSR1FFAR1FFAR4PTGER1PTGER4 | |
| SCHEMBL455219 | 0.81 | FFAR1 (0.59) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL30288127 | 0.81 | FFAR1 (0.59) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL9997112 | 0.80 | IAPP (0.51) | NPSR1FFAR1FFAR4PTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020119592-A1 | NOVEL THREE-RING FUSED STRUCTURE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 信达生物制药(苏州)有限公司 | 2020-06-18 | — | — | WO | disclosed |