SCHEMBL455219

SCHEMBL455219

O=C(O)CCc1ccccc1Cl

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.59
PLAAT3 P53816 2/20 0.55
PLAAT5 Q96KN8 2/20 0.55
PLAAT2 Q9NWW9 2/20 0.55
PLAAT4 Q9UL19 2/20 0.55
PTGER1 P34995 2/20 0.54
PTGER4 P35408 2/20 0.54
PTGER3 P43115 2/20 0.54
PTGER2 P43116 2/20 0.54
KEAP1 Q14145 1/20 0.54
TAAR1 Q96RJ0 1/20 0.52
FFAR4 Q5NUL3 1/20 0.51
HIF1A Q16665 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
CTBP2 P56545 1/20 0.49
CASP3 P42574 1/20 0.48
CASP7 P55210 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
CXCL8 P10145 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30288127 1.00 FFAR1 (0.59) FFAR1PLAAT3PLAAT5PLAAT2PLAAT4
Hydrochloric Acid SCHEMBL16239236 0.98 FFAR1 (0.58) FFAR1PLAAT3PLAAT5PLAAT2PLAAT4
Ethane SCHEMBL10497410 0.96 FFAR1 (0.56) FFAR1PLAAT3PLAAT5PLAAT2PLAAT4
SCHEMBL30861873 0.88 HDAC3 (0.57) FFAR1PLAAT3PLAAT5PLAAT2PLAAT4
SCHEMBL2316238 0.88 HDAC3 (0.57) FFAR1PLAAT3PLAAT5PLAAT2PLAAT4
SCHEMBL18112923 0.86 MAPT (0.56) FFAR1PLAAT3PLAAT5PLAAT2PLAAT4
SCHEMBL7331092 0.85 TAAR1 (0.54) PLAAT3PLAAT5PLAAT2PLAAT4TAAR1
SCHEMBL27438258 0.85 MAPT (0.59) FFAR1PLAAT3PLAAT5PLAAT2PLAAT4
SCHEMBL27413118 0.85 MAPT (0.59) FFAR1PLAAT3PLAAT5PLAAT2PLAAT4
SCHEMBL27437588 0.85 MAPT (0.59) FFAR1PLAAT3PLAAT5PLAAT2PLAAT4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116987034-A 5- ((4-chloro-2, 3-dihydro-1H-inden-1-yl) methyl) -1H-imidazole and synthetic method thereof 安徽大学 2023-11-03 CN claimed
US-20160168306-A1 NOVEL COMPOSITIONS AND METHODS TO PRODUCE TRIAZINE-ARYLHYDROXY-ALDEHYDE CONDENSATES WITH IMPROVED SOLUBILITY WILMINGTON SAVINGS FUND SOCIETY, FSB, AS THE CURRENT COLLATERAL AGENT 2016-06-16 US claimed
EP-1282680-A1 COMPOSITIONS COMPRISING CYCLODEXTRIN THE PROCTER & GAMBLE COMPANY (US) 2003-02-12 EP claimed
US-6503413-B2 Polyalkylene polysiloxane, buffering agent, aqueous carrier THE PROCTER & GAMBLE COMPANY 2003-01-07 US claimed
EP-1255806-A1 STABLE, AQUEOUS COMPOSITIONS FOR TREATING SURFACES, ESPECIALLY FABRICS THE PROCTER & GAMBLE COMPANY (US) 2002-11-13 EP claimed
US-20020011584-A1 Stable, aqueous compositions for treating surfaces, especially fabrics THE PROCTOR & GAMBLE COMPANY 2002-01-31 US claimed
US-20020010154-A1 Compositions comprising cyclodextrin THE PROCTER & GAMBLE COMPANY 2002-01-24 US claimed
WO-2001088076-A1 COMPOSITIONS COMPRISING CYCLODEXTRIN THE PROCTER & GAMBLE COMPANY (US) 2001-11-22 WO claimed
US-6289286-B1 Surface regeneration of biosensors and characterization of biomolecules associated therewith BIACORE AB (SE) 2001-09-11 US claimed
WO-2001060961-A1 STABLE, AQUEOUS COMPOSITIONS FOR TREATING SURFACES, ESPECIALLY FABRICS THE PROCTER & GAMBLE COMPANY (US) 2001-08-23 WO claimed
EP-1082607-A1 SURFACE REGENERATION OF BIOSENSORS Biacore AB (SE) 2001-03-14 EP claimed
WO-1999063333-A1 SURFACE REGENERATION OF BIOSENSORS BIACORE AB (SE) 1999-12-09 WO claimed
US-5648540-A Amine preparation NPS PHARMACEUTICALS, INC. (US) 1997-07-15 US claimed
WO-1996002492-A1 METHOD OF MAKING A BENZYLPROPANAMINE NSP PHARMACEUTICALS, INC. (US) 1996-02-01 WO claimed
EP-0451201-A1 PREPARATION OF BIDENTATE LIGANDS EASTMAN KODAK COMPANY (US) 1991-10-16 EP claimed
WO-1990006930-A1 PREPARATION OF BIDENTATE LIGANDS EASTMAN KODAK COMPANY (US) 1990-06-28 WO claimed
EP-0375576-A1 Preparation of bidentate ligands EASTMAN KODAK COMPANY (US) 1990-06-27 EP claimed
US-4390723-A BIS(8-QUINOLINOLATE) COPPER COMPLEX CATALYST IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1983-06-28 US claimed
JP-9328473-A None JP disclosed
US-4065574-A New method for controlling fungi using 4-chromone, 4-chromanone, 4-chromone oxime and 4-chromanone oxime compounds THE UPJOHN COMPANY (US) 1977-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020010154-A1 Compositions comprising cyclodextrin FFAR4, FRG1, FGB FFAR1 4/4885PLAAT3 1629/4885PLAAT5 2837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.