Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 10/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29569795 | 0.87 | MAT2A (0.53) | MAT2ACSF1RPRMT5TRPV6 | |
| SCHEMBL22103376 | 0.87 | MAT2A (0.53) | MAT2ACSF1RPRMT5TRPV6 | |
| SCHEMBL29571135 | 0.86 | MAT2A (0.43) | MAT2ACSF1RGAAPRMT5TRPV6 | |
| SCHEMBL22093108 | 0.86 | MAT2A (0.43) | MAT2ACSF1RGAAPRMT5TRPV6 | |
| SCHEMBL22103156 | 0.73 | MAT2A (0.66) | MAT2APRMT5 | |
| SCHEMBL29571509 | 0.73 | MAT2A (0.66) | MAT2APRMT5 | |
| SCHEMBL29571058 | 0.72 | MAT2A (0.59) | MAT2APIK3CA | |
| SCHEMBL22103154 | 0.72 | MAT2A (0.59) | MAT2APIK3CA | |
| SCHEMBL22094109 | 0.71 | MAT2A (0.63) | MAT2A | |
| SCHEMBL29570516 | 0.71 | MAT2A (0.63) | MAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020123395-A1 | 2-OXOQUINAZOLINE DERIVATIVES AS METHIONINE ADENOSYLTRANSFERASE 2A INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2020-06-18 | — | — | WO | disclosed |