Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 18/20 | 0.51 |
| ▸ | MAT1A | Q00266 | 1/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22103252 | 1.00 | MAT2A (0.51) | MAT2AMAT1AHCAR1 | |
| SCHEMBL29570494 | 1.00 | MAT2A (0.51) | MAT2AMAT1AHCAR1 | |
| SCHEMBL22093224 | 0.87 | MAT2A (0.68) | MAT2AHCAR1 | |
| SCHEMBL22093222 | 0.87 | MAT2A (0.68) | MAT2AHCAR1 | |
| SCHEMBL22103255 | 0.87 | MAT2A (0.68) | MAT2AHCAR1 | |
| SCHEMBL22103256 | 0.87 | MAT2A (0.68) | MAT2AHCAR1 | |
| SCHEMBL22093838 | 0.85 | MAT2A (0.57) | MAT2AHCAR1 | |
| SCHEMBL31145512 | 0.85 | MAT2A (0.57) | MAT2AHCAR1 | |
| SCHEMBL23734087 | 0.84 | MAT2A (0.51) | MAT2AMAT1AHCAR1 | |
| SCHEMBL22103374 | 0.84 | MAT2A (0.51) | MAT2AMAT1AHCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020123395-A1 | 2-OXOQUINAZOLINE DERIVATIVES AS METHIONINE ADENOSYLTRANSFERASE 2A INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2020-06-18 | — | — | WO | disclosed |