Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 17/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22103363 | 0.96 | MAT2A (0.59) | MAT2ATP53MAPTTLR7 | |
| SCHEMBL22093438 | 0.88 | MAT2A (0.72) | MAT2A | |
| SCHEMBL29571042 | 0.88 | MAT2A (0.72) | MAT2A | |
| SCHEMBL22103000 | 0.85 | MAT2A (0.57) | MAT2A | |
| SCHEMBL22103546 | 0.85 | MAT2A (0.57) | MAT2A | |
| SCHEMBL23583455 | 0.85 | MAT2A (0.57) | MAT2A | |
| SCHEMBL30894483 | 0.85 | MAT2A (0.57) | MAT2A | |
| SCHEMBL22103169 | 0.85 | MAT2A (0.57) | MAT2A | |
| SCHEMBL22093380 | 0.85 | MAT2A (0.57) | MAT2A | |
| SCHEMBL22093381 | 0.85 | MAT2A (0.57) | MAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020123395-A1 | 2-OXOQUINAZOLINE DERIVATIVES AS METHIONINE ADENOSYLTRANSFERASE 2A INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2020-06-18 | — | — | WO | disclosed |