Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 11/20 | 0.49 |
| ▸ | AGER | Q15109 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | WHR1 | P49842 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22103357 | 0.96 | MAT2A (0.51) | MAT2AADORA2AADORA1ABCG2USP2 | |
| SCHEMBL22093113 | 0.87 | MAT2A (0.49) | MAT2AABCG2USP2TSHRHSD17B10 | |
| SCHEMBL22103567 | 0.87 | MAT2A (0.49) | MAT2AABCG2USP2TSHRHSD17B10 | |
| SCHEMBL22103571 | 0.87 | MAT2A (0.49) | MAT2AABCG2USP2TSHRHSD17B10 | |
| SCHEMBL22093111 | 0.87 | MAT2A (0.49) | MAT2AABCG2USP2TSHRHSD17B10 | |
| SCHEMBL22103408 | 0.87 | MAT2A (0.49) | MAT2AABCG2USP2TSHRHSD17B10 | |
| SCHEMBL22103576 | 0.87 | MAT2A (0.49) | MAT2AABCG2USP2TSHRHSD17B10 | |
| SCHEMBL22093580 | 0.86 | MAT2A (0.47) | MAT2AADORA2AADORA1ABCG2USP2 | |
| SCHEMBL22093579 | 0.86 | MAT2A (0.47) | MAT2AADORA2AADORA1ABCG2USP2 | |
| SCHEMBL22093259 | 0.85 | MAT2A (0.55) | MAT2AABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020123395-A1 | 2-OXOQUINAZOLINE DERIVATIVES AS METHIONINE ADENOSYLTRANSFERASE 2A INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2020-06-18 | — | — | WO | disclosed |