Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 13/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22093507 | 0.91 | MAT2A (0.50) | MAT2AABCG2BRD4ALDH1A1 | |
| SCHEMBL22093252 | 0.91 | MAT2A (0.50) | MAT2ATLR7CYP1A2ABCG2ALDH1A1 | |
| SCHEMBL29570761 | 0.91 | MAT2A (0.50) | MAT2ATLR7CYP1A2ABCG2ALDH1A1 | |
| SCHEMBL22103390 | 0.87 | MAT2A (0.50) | MAT2ATLR7ABCG2BRD4 | |
| SCHEMBL29570999 | 0.87 | MAT2A (0.55) | MAT2AABCG2 | |
| SCHEMBL22093259 | 0.87 | MAT2A (0.55) | MAT2AABCG2 | |
| SCHEMBL22093149 | 0.87 | MAT2A (0.49) | MAT2AABCG2BRD4 | |
| SCHEMBL29571198 | 0.87 | MAT2A (0.49) | MAT2AABCG2BRD4 | |
| SCHEMBL22093152 | 0.87 | MAT2A (0.49) | MAT2AABCG2BRD4 | |
| SCHEMBL22093271 | 0.86 | MAT2A (0.48) | MAT2ATLR7ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020123395-A1 | 2-OXOQUINAZOLINE DERIVATIVES AS METHIONINE ADENOSYLTRANSFERASE 2A INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2020-06-18 | — | — | WO | disclosed |