SCHEMBL2210399

SCHEMBL2210399

CCOc1cc(N)ccc1-c1ccc(N)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.56
KDM4E B2RXH2 4/20 0.56
GAA P10253 4/20 0.56
ALDH1A1 P00352 5/20 0.52
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
MAPK1 P28482 3/20 0.52
POLB P06746 3/20 0.52
HSD17B10 Q99714 3/20 0.52
HPGD P15428 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
TSHR P16473 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
PTPRC P08575 1/20 0.44
TP53 P04637 3/20 0.43
CYP3A4 P08684 1/20 0.43
CASP1 P29466 2/20 0.42
CASP7 P55210 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
ALOX15 P16050 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30427138 1.00 MAPT (0.56) MAPTKDM4EGAAALDH1A1MEN1
SCHEMBL3783390 0.89 MAPT (0.53) MAPTKDM4EGAAALDH1A1MEN1
SCHEMBL19777591 0.89 MAPT (0.55) MAPTKDM4EGAAALDH1A1MEN1
SCHEMBL347279 0.88 MAPT (0.63) MAPTKDM4EGAAALDH1A1MEN1
SCHEMBL3780933 0.85 MAPT (0.56) MAPTKDM4EGAAALDH1A1MEN1
SCHEMBL3790341 0.84 MAPT (0.51) MAPTKDM4EGAAALDH1A1MEN1
Hydrochloric Acid SCHEMBL28541885 0.84 GAA (0.60) MAPTKDM4EGAAALDH1A1MEN1
SCHEMBL10337464 0.83 TSHR (0.47) MAPTKDM4EGAAALDH1A1MEN1
SCHEMBL3793772 0.81 PTPRC (0.55) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL10021510 0.80 MAPT (0.54) MAPTKDM4EGAAALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014004146-A1 SILICONE RUBBER EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-01-03 WO claimed
WO-2005017485-A2 MULTIPLEX ENZYME-LINKED IMMUNOSORBENT ASSAY FOR DETECTING MULTIPLE ANALYTES AGDIA, INC. (US) 2005-02-24 WO claimed
WO-1994012621-A1 ENHANCEMENT OF ENZYME REACTIONS NOVO NORDISK (DK) 1994-06-09 WO claimed
EP-3202849-B1 FLOWABILITY IMPROVER FOR POLYCARBONATE AND POLYARYLATE, POLYCARBONATE RESIN COMPOSITION, POLYARYLATE RESIN COMPOSITION, AND MOLDED ARTICLE THEREOF KANEKA CORP (JP) 2020-05-13 EP disclosed
EP-3395894-B1 RESIN COMPOSITION AND ADHESIVE SHEET KANEKA CORP (JP) 2020-04-15 EP disclosed
US-10619004-B2 Flowability enhancing agent for polycarbonate resin, method for producing said agent, polycarbonate resin composition and molded article thereof KANEKA CORPORATION (JP) 2020-04-14 US disclosed
US-20200062893-A1 FLOWABILITY ENHANCING AGENT FOR POLYCARBONATE RESIN, METHOD FOR PRODUCING SAID AGENT, POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF KANEKA CORPORATION (JP) 2020-02-27 US disclosed
US-20200040180-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF KANEKA CORPORATION (JP) 2020-02-06 US disclosed
US-20190119490-A1 RESIN COMPOSITION, MOULDED ARTICLE, AND PLATED MOULDED ARTICLE KANEKA CORPORATION (JP) 2019-04-25 US disclosed
EP-2824131-B1 THERMALLY CONDUCTIVE RESIN MOLDED ARTICLE AND METHOD FOR MANUFACTURING THERMALLY CONDUCTIVE RESIN MOLDED ARTICLE KANEKA CORP (JP) 2019-04-24 EP disclosed
US-10253178-B2 Flowability improver for polycarbonate and polyarylate, polycarbonate resin composition, polyarylate resin composition, and molded article thereof KANEKA CORPORATION (JP) 2019-04-09 US disclosed
EP-1343834-A2 THE ENCAPSULATION OF ACTIVES IN CORE-SHELL AND GEL PARTICLES Dow Corning Corporation (US) 2003-09-17 EP disclosed
WO-2003033528-A1 CYCLIC PEPTIDES AS G-PROTEIN-COUPLED RECEPTOR ANTAGONISTS UNIVERSITY OF QUEENSLAND (AU) 2003-04-24 WO disclosed
US-20030050393-A1 Encapsulation of actives in core-shell and gel particles DOW CORNING CORPORATION 2003-03-13 US disclosed
WO-2002059211-A2 SILICONE ELASTOMER COMPOSITIONS DOW CORNING CORPORATION (US) 2002-08-01 WO disclosed
US-20020086935-A1 Silicone elastomer compositions DOW CORNING CORPORATION 2002-07-04 US disclosed
WO-2002050166-A2 THE ENCAPSULATION OF ACTIVES IN CORE-SHELL AND GEL PARTICLES DOW CORNING CORPORATION (US) 2002-06-27 WO disclosed
US-6388045-B1 CARBOXYLATED AROMATIC COMPOUND KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2002-05-14 US disclosed
US-20020045728-A1 Aromatic dicarboxylic acid composition and liquid crystalline polyester resin made from the same KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO 2002-04-18 US disclosed
EP-1103573-A1 LIQUID-CRYSTAL POLYMER KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2001-05-30 EP disclosed