SCHEMBL22105926

SCHEMBL22105926

CC(C)(CCOC(C)(C)CC(=O)O)NC(=O)CC(C)(C)OCCC(C)(C)NC(=O)c1cnc(NSc2ccc(Oc3ccc(F)c(C(C)(C)CC(C)(C)C(=O)O)c3)cc2)nc1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ EGLN2 Q96KS0 2/20 0.32
▸ EGLN1 Q9GZT9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24257929 0.88 TDP1 (0.34) EGLN2EGLN1
SCHEMBL24257939 0.82 TDP1 (0.33) EGLN2
SCHEMBL24257955 0.78 TDP1 (0.30) —
SCHEMBL24257952 0.76 — —
SCHEMBL24257942 0.72 TDP1 (0.39) —
SCHEMBL24257947 0.68 TDP1 (0.35) —
SCHEMBL24257917 0.66 HDAC3 (0.39) —
SCHEMBL22079960 0.66 TDP1 (0.40) —
SCHEMBL24257721 0.63 TDP1 (0.34) —
SCHEMBL22106128 0.62 CYP4F2 (0.34) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020120463-A1 INSULIN CONJUGATES SANOFI (FR) 2020-06-18 — — WO disclosed
Send feedback