Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24257929 | 0.93 | TDP1 (0.34) | TDP1EGLN2POLB | |
| SCHEMBL24257955 | 0.84 | TDP1 (0.30) | TDP1 | |
| SCHEMBL24257952 | 0.82 | — | — | |
| SCHEMBL22105926 | 0.82 | EGLN2 (0.32) | EGLN2 | |
| SCHEMBL24257942 | 0.78 | TDP1 (0.39) | TDP1POLB | |
| SCHEMBL24257947 | 0.75 | TDP1 (0.35) | TDP1POLB | |
| SCHEMBL22079960 | 0.72 | TDP1 (0.40) | TDP1POLB | |
| SCHEMBL24257917 | 0.71 | HDAC3 (0.39) | TDP1 | |
| SCHEMBL24257969 | 0.70 | TDP1 (0.44) | TDP1POLB | |
| SCHEMBL22079886 | 0.69 | TDP1 (0.43) | TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048968-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048968-A1 | INSULIN CONJUGATES | IAPP, INSR, IGF1R | TDP1 4783/4885EGLN2 1447/4885POLB 4107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.