Spr-741

Spr-741

SCHEMBL22106115

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nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 3/20 0.75
▸ RCOR1 Q9UKL0 2/20 0.75
▸ SSTR5 P35346 6/20 0.45
▸ SSTR2 P30874 5/20 0.45
▸ SSTR4 P31391 5/20 0.45
▸ TERF2IP Q9NYB0 4/20 0.43
▸ KEAP1 Q14145 1/20 0.42
▸ KLK7 P49862 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Spr-741 SCHEMBL21116156 1.00 KDM1A (0.75) KDM1ARCOR1SSTR5SSTR2SSTR4
Spr-741 SCHEMBL21335177 1.00 KDM1A (0.75) KDM1ARCOR1SSTR5SSTR2SSTR4
Spr-741 SCHEMBL19545979 1.00 KDM1A (0.75) KDM1ARCOR1SSTR5SSTR2SSTR4
SCHEMBL19545834 0.96 KDM1A (0.69) KDM1ARCOR1SSTR5SSTR2SSTR4
SCHEMBL19545985 0.94 KDM1A (0.73) KDM1ARCOR1SSTR5SSTR2SSTR4
SCHEMBL19545838 0.94 KDM1A (0.73) KDM1ARCOR1SSTR5SSTR2SSTR4
SCHEMBL19545596 0.93 KDM1A (0.73) KDM1ARCOR1SSTR5SSTR2SSTR4
SCHEMBL19546032 0.92 KDM1A (0.72) KDM1ARCOR1SSTR5SSTR2SSTR4
SCHEMBL17992355 0.92 KDM1A (0.73) KDM1ARCOR1SSTR5SSTR2SSTR4
SCHEMBL19546019 0.92 KDM1A (0.70) KDM1ARCOR1SSTR5SSTR2SSTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200188476-A1 ANTI-MICROBIAL AGENT-POLYMER CONJUGATES AND METHODS OF USE THEREOF UNIV CALIFORNIA (US) 2020-06-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200188476-A1 ANTI-MICROBIAL AGENT-POLYMER CONJUGATES AND METHODS OF USE THEREOF DDOST, MGAM, MSN KDM1A 3829/4885RCOR1 4860/4885SSTR5 2094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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