SCHEMBL22106586

SCHEMBL22106586

Cc1ccc(C#N)cc1-c1cc2c3cc4ccccc4cc3n3c4c(C)c5ccccc5cc4c(c1)c23

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ENPP3 O14638 1/20 0.39
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
XDH P47989 1/20 0.33
SLC22A12 Q96S37 1/20 0.33
PTGER4 P35408 1/20 0.32
ABL1 P00519 2/20 0.32
CHEK1 O14757 1/20 0.31
EGFR P00533 1/20 0.31
PDPK1 O15530 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30
TSHR P16473 1/20 0.30
AR P10275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19563785 0.91 ENPP3 (0.38) ENPP3CA1CA2CYP11B1CYP11B2
SCHEMBL21710470 0.89 ENPP3 (0.40) ENPP3CA1CA2CYP11B1CYP11B2
SCHEMBL21717870 0.83 ENPP3 (0.39) ENPP3CA1CA2CYP11B1CYP11B2
SCHEMBL19563848 0.82 ENPP3 (0.38) ENPP3CA1CA2CYP11B1CYP11B2
SCHEMBL21717346 0.80 PTGER4 (0.37) ENPP3CA1CA2CYP11B1CYP11B2
SCHEMBL22088254 0.79 PTGER4 (0.34) ENPP3CYP11B1CYP11B2PTGER4ABL1
SCHEMBL22088217 0.78 KDM4E (0.35) CYP11B1CYP11B2PTGER4CHEK1TSHR
SCHEMBL21710482 0.77 PTGER4 (0.38) ENPP3CA1CA2CYP11B1CYP11B2
SCHEMBL19563987 0.77 CYP11B1 (0.35) CYP11B1CYP11B2ABL1CHEK1
SCHEMBL19563808 0.77 PTGDR2 (0.39) ENPP3CA1CA2CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3269720-B1 NOVEL COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC APPLIANCE IDEMITSU KOSAN CO (JP) 2020-06-17 EP disclosed