Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 5/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.52 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.37 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.31 |
| ▸ | NMT1 | P30419 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.30 |
| ▸ | CDK9 | P50750 | 2/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30460151 | 0.88 | SLCO1B1 (0.42) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL19715489 | 0.85 | SLCO1B1 (0.71) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL29411772 | 0.81 | SLCO1B1 (0.58) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL28631662 | 0.81 | SLCO1B1 (0.56) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL21807864 | 0.81 | SLCO1B1 (0.56) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL22108733 | 0.81 | SLCO1B1 (0.48) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL22108233 | 0.81 | SLCO1B1 (0.66) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL22108262 | 0.81 | SLCO1B1 (0.66) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL21796139 | 0.81 | SLCO1B1 (0.48) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL23863735 | 0.80 | SLCO1B1 (0.79) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666771-B1 | LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-09-29 | — | — | EP | disclosed |
| EP-3666771-A1 | LPA ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2020-06-17 | — | — | EP | disclosed |