Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 4/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.48 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.35 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19715709 | 0.88 | SLCO1B1 (0.66) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL19715615 | 0.86 | SLCO1B1 (0.38) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL19715607 | 0.86 | SLCO1B1 (0.39) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL29411747 | 0.85 | SLCO1B1 (0.55) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL19728938 | 0.85 | SLCO1B1 (0.55) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL22108342 | 0.81 | SLCO1B1 (0.52) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL24982985 | 0.81 | SLCO1B1 (0.39) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL29068103 | 0.79 | SLCO1B1 (0.36) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL30452478 | 0.79 | SLCO1B1 (0.36) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL19715601 | 0.79 | SLCO1B1 (0.36) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666771-A1 | LPA ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2020-06-17 | — | — | EP | disclosed |