Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adenosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 known ✓ | P30542 | 3/20 | 0.80 |
| ▸ | ADORA3 known ✓ | P0DMS8 | 1/20 | 0.80 |
| ▸ | ADORA2A known ✓ | P29274 | 1/20 | 0.80 |
| ▸ | ADORA2B known ✓ | P29275 | 1/20 | 0.80 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.80 |
| ▸ | DPP4 | P27487 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.80 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.80 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.80 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.80 |
| ▸ | GAPDH | P04406 | 1/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.80 |
| ▸ | STAT6 | P42226 | 1/20 | 0.80 |
| ▸ | PI4KA | P42356 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.80 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.80 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.80 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.80 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenosine SCHEMBL29796534 | 1.00 | P2RY2 (0.82) | P2RY2ADORA1SMN1; SMN2DPP4MEN1 | |
| Vidarabine SCHEMBL7170349 | 1.00 | P2RY2 (0.82) | P2RY2ADORA1SMN1; SMN2DPP4MEN1 | |
| Adenosine SCHEMBL1744580 | 1.00 | P2RY2 (0.82) | P2RY2ADORA1SMN1; SMN2DPP4MEN1 | |
| Adenosine SCHEMBL29397260 | 1.00 | P2RY2 (0.82) | P2RY2ADORA1SMN1; SMN2DPP4MEN1 | |
| Adenosine SCHEMBL459770 | 0.99 | P2RY2 (0.80) | P2RY2ADORA1SMN1; SMN2DPP4MEN1 | |
| Adenosine SCHEMBL29362201 | 0.99 | P2RY2 (0.80) | P2RY2ADORA1SMN1; SMN2DPP4MEN1 | |
| Adenosine SCHEMBL28296801 | 0.99 | P2RY2 (0.80) | P2RY2ADORA1SMN1; SMN2DPP4MEN1 | |
| Adenosine SCHEMBL459996 | 0.99 | P2RY2 (0.80) | P2RY2ADORA1SMN1; SMN2DPP4MEN1 | |
| Adenosine SCHEMBL28186074 | 0.99 | P2RY2 (0.80) | P2RY2ADORA1SMN1; SMN2DPP4MEN1 | |
| Adenosine SCHEMBL28240733 | 0.99 | P2RY2 (0.80) | P2RY2ADORA1SMN1; SMN2DPP4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109369963-A | A kind of method that useless diacetate fiber prepares diacetate fiber micelle | 济南大自然新材料有限公司 | 2019-02-22 | — | — | CN | claimed |
| CN-108753808-A | A kind of recombinant expression carrier, recombinant expression host and its method for synthesizing adenosine triphosphoric acid | 浙江海正药业股份有限公司 | 2018-11-06 | — | — | CN | claimed |
| CN-108368493-A | Enzymatic system and method for synthesizing nicotinamide mononucleotide and niacin mononucleotide | 新南创新私人有限公司 | 2018-08-03 | — | — | CN | claimed |
| CN-106480165-A | Mensure reagent of 1,5 dewatered grape sugar alcohols and preparation method thereof | 浙江达美生物技术有限公司 | 2017-03-08 | — | — | CN | claimed |
| CN-105954221-A | Method for quantitatively determining shares of glycolysis pathway and shares of pentose phosphate pathway in plant glucose metabolism | 中国科学院地球化学研究所 | 2016-09-21 | — | — | CN | claimed |
| WO-2007075151-A1 | COMPOSITE VASODILATOR BASED ON A NO-GROUP DONATOR AND A PROMOTER | KUTNYAK VICTOR PAVLOVICH (UA) | 2007-07-05 | — | — | WO | claimed |
| CN-1382699-A | Polypeptide-nuclear triphosphoddenosine bindin-30.47 and polynucleotide for coding it | BIOWINDOW GENE DEV INC (CN) | 2002-12-04 | — | — | CN | claimed |
| US-5059526-A | Storage stability, accuracy | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1991-10-22 | — | — | US | claimed |
| US-4833075-A | Immobilized luciferase for the quantitative determination of ATP | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1989-05-23 | — | — | US | claimed |
| JP-55108297-A | — | — | None | — | — | JP | disclosed |
| JP-53118592-A | — | — | None | — | — | JP | disclosed |
| JP-53118592-A | — | — | None | — | — | JP | disclosed |
| JP-1320998-A | — | — | None | — | — | JP | disclosed |
| JP-8099860-A | — | — | None | — | — | JP | disclosed |
| JP-S53118592-A | PREPARATION OF HIGH PURITY ADENOSINE TRIPHOSPHORIC ACID AQUEOUS SOLUTION | DAI ICHI SEIYAKU CO LTD | 1978-10-17 | — | — | JP | disclosed |
| JP-S536490-A | PREPARATION OF HIGH PURITY ADENOSINE TRIPHOSPHORIC ACID | DAI ICHI SEIYAKU CO LTD | 1978-01-20 | — | — | JP | disclosed |
| JP-S536490-A | PREPARATION OF HIGH PURITY ADENOSINE TRIPHOSPHORIC ACID | DAI ICHI SEIYAKU CO LTD | 1978-01-20 | — | — | JP | disclosed |
| US-4057535-A | POLYURETHANE | LIPATOVA TATYANA ESPEROVNA | 1977-11-08 | — | — | US | disclosed |
| US-4044122-A | SODIUM SALT OF ADENYLIC ACID | SKLAR S HARVEY | 1977-08-23 | — | — | US | disclosed |
| JP-H00453494-A | — | — | 0001-01-01 | — | — | JP | disclosed |