Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adenosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 known ✓ | P30542 | 3/20 | 0.80 |
| ▸ | ADORA3 known ✓ | P0DMS8 | 1/20 | 0.80 |
| ▸ | ADORA2A known ✓ | P29274 | 1/20 | 0.80 |
| ▸ | ADORA2B known ✓ | P29275 | 1/20 | 0.80 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.80 |
| ▸ | DPP4 | P27487 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.80 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.80 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.80 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.80 |
| ▸ | GAPDH | P04406 | 1/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.80 |
| ▸ | STAT6 | P42226 | 1/20 | 0.80 |
| ▸ | PI4KA | P42356 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.80 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.80 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.80 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.80 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vidarabine SCHEMBL7170349 | 1.00 | P2RY2 (0.82) | P2RY2ADORA1SMN1; SMN2DPP4MEN1 | |
| Adenosine SCHEMBL1744580 | 1.00 | P2RY2 (0.82) | P2RY2ADORA1SMN1; SMN2DPP4MEN1 | |
| Adenosine SCHEMBL29397260 | 1.00 | P2RY2 (0.82) | P2RY2ADORA1SMN1; SMN2DPP4MEN1 | |
| Adenosine SCHEMBL2210868 | 1.00 | P2RY2 (0.82) | P2RY2ADORA1SMN1; SMN2DPP4MEN1 | |
| Adenosine SCHEMBL459770 | 0.99 | P2RY2 (0.80) | P2RY2ADORA1SMN1; SMN2DPP4MEN1 | |
| Adenosine SCHEMBL29362201 | 0.99 | P2RY2 (0.80) | P2RY2ADORA1SMN1; SMN2DPP4MEN1 | |
| Adenosine SCHEMBL28296801 | 0.99 | P2RY2 (0.80) | P2RY2ADORA1SMN1; SMN2DPP4MEN1 | |
| Adenosine SCHEMBL459996 | 0.99 | P2RY2 (0.80) | P2RY2ADORA1SMN1; SMN2DPP4MEN1 | |
| Adenosine SCHEMBL28186074 | 0.99 | P2RY2 (0.80) | P2RY2ADORA1SMN1; SMN2DPP4MEN1 | |
| Adenosine SCHEMBL28240733 | 0.99 | P2RY2 (0.80) | P2RY2ADORA1SMN1; SMN2DPP4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121628874-B | EC riboflavin kinase mutant and application thereof | 深圳希吉亚生物技术有限公司 | 2026-05-15 | — | — | CN | claimed |
| WO-2025071557-A1 | COLLOIDAL SUSPENSION OF NUTRACEUTICAL INGREDIENTS TO TREAT TRAUMATIC BRAIN INJURY | CHITTENDEN ROBERT AUSTIN (US) | 2025-04-03 | — | — | WO | claimed |
| US-20250099382-A1 | Colloidal suspension of nutraceutical ingredients to treat traumatic brain injury | CHITTENDEN ROBERT AUSTIN (US) | 2025-03-27 | — | — | US | claimed |
| CN-116411038-A | Method for preparing nicotinamide adenine dinucleotide phosphate by using enzyme method | 湖南利尔生物科技有限公司 | 2023-07-11 | — | — | CN | claimed |
| CN-121628874-B | EC riboflavin kinase mutant and application thereof | 深圳希吉亚生物技术有限公司 | 2026-05-15 | — | — | CN | disclosed |
| WO-2025071557-A1 | COLLOIDAL SUSPENSION OF NUTRACEUTICAL INGREDIENTS TO TREAT TRAUMATIC BRAIN INJURY | CHITTENDEN ROBERT AUSTIN (US) | 2025-04-03 | — | — | WO | disclosed |
| WO-2025071557-A1 | COLLOIDAL SUSPENSION OF NUTRACEUTICAL INGREDIENTS TO TREAT TRAUMATIC BRAIN INJURY | CHITTENDEN ROBERT AUSTIN (US) | 2025-04-03 | — | — | WO | disclosed |
| US-20250099382-A1 | Colloidal suspension of nutraceutical ingredients to treat traumatic brain injury | CHITTENDEN ROBERT AUSTIN (US) | 2025-03-27 | — | — | US | disclosed |
| US-20250099382-A1 | Colloidal suspension of nutraceutical ingredients to treat traumatic brain injury | CHITTENDEN ROBERT AUSTIN (US) | 2025-03-27 | — | — | US | disclosed |
| CN-116411038-A | Method for preparing nicotinamide adenine dinucleotide phosphate by using enzyme method | 湖南利尔生物科技有限公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-116411038-A | Method for preparing nicotinamide adenine dinucleotide phosphate by using enzyme method | 湖南利尔生物科技有限公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-115583982-A | Amine modified adenosine triphosphate flame retardant, preparation method thereof and application thereof in fireproof coating | 武汉工程大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-110947034-B | Bioactive calcium phosphate/fibrin compounded injectable bone repair hydrogel | 上海市第十人民医院 | 2022-05-27 | — | — | CN | disclosed |