Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10833224 | 1.00 | CYP1A2 (0.45) | CYP1A2PKMMEN1KMT2AHTT | |
| SCHEMBL8754355 | 0.94 | CYP1A2 (0.41) | CYP1A2PKMMEN1KMT2AHTT | |
| SCHEMBL2211195 | 0.94 | CYP1A2 (0.41) | CYP1A2PKMMEN1KMT2AHTT | |
| SCHEMBL9060505 | 0.94 | CYP1A2 (0.41) | CYP1A2PKMMEN1KMT2AHTT | |
| SCHEMBL8753758 | 0.94 | CYP1A2 (0.52) | CYP1A2PKMMEN1KMT2AHTT | |
| SCHEMBL8755857 | 0.92 | CYP1A2 (0.50) | CYP1A2PKMMEN1KMT2AHTT | |
| SCHEMBL8755860 | 0.92 | CYP1A2 (0.50) | CYP1A2PKMMEN1KMT2AHTT | |
| SCHEMBL8755867 | 0.92 | CYP1A2 (0.50) | CYP1A2PKMMEN1KMT2AHTT | |
| SCHEMBL1249367 | 0.88 | CYP1A2 (0.47) | CYP1A2PKMMEN1KMT2AHTT | |
| SCHEMBL2207128 | 0.85 | CYP2C9 (0.36) | CYP1A2MEN1KMT2ACYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9605207-B2 | Orthoester derivative, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2017-03-28 | — | — | US | disclosed |
| CN-103443104-B | There is compound, liquid-crystal composition and the liquid crystal display cells of 2,6,7-trioxa-l-phosphabicyclo [2.2.2] octane ring | 捷恩智株式会社 | 2016-08-10 | — | — | CN | disclosed |
| CN-101035779-B | Tetrahydropyran mixture, liquid crystal composition and liquid crystal display element containing the same | JNC CORP | 2015-06-03 | — | — | CN | disclosed |
| EP-2690103-A1 | ORTHO ESTER DERIVATIVE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC Corporation (JP) | 2014-01-29 | — | — | EP | disclosed |
| US-20140021407-A1 | ORTHOESTER DERIVATIVE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2014-01-23 | — | — | US | disclosed |
| EP-2128149-B1 | Tetrahydrofuran compound, liquid crystal composition and liquid crystal display device containing the liquid crystal composition | JNC CORP (JP) | 2013-07-24 | — | — | EP | disclosed |
| EP-1798228-B1 | TETRAHYDROPYRAN COMPOUNDS, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAYS CONTAINING THE COMPOSITIONS | JNC CORP (JP) | 2012-11-14 | — | — | EP | disclosed |
| US-7981486-B2 | Compound having alkyl on benzene ring, liquid crystal composition having the compound, and liquid crystal display device having the liquid crystal composition | JNC CORPORATION (JP) | 2011-07-19 | — | — | US | disclosed |
| US-7981486-B2 | Compound having alkyl on benzene ring, liquid crystal composition having the compound, and liquid crystal display device having the liquid crystal composition | JNC CORPORATION (JP) | 2011-07-19 | — | — | US | disclosed |
| US-7846513-B2 | Compound having alkyl on benzene ring, liquid crystal composition having the compound, and liquid crystal display device having the liquid crystal composition | CHISSO CORPORATION (JP) | 2010-12-07 | — | — | US | disclosed |
| EP-1798228-A1 | TETRAHYDROPYRAN COMPOUNDS, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAYS CONTAINING THE COMPOSITIONS | CHISSO CORPORATION (JP) | 2007-06-20 | — | — | EP | disclosed |
| US-20060097226-A1 | Compound having alkyl on benzene ring, liquid crystal composition having the compound, and liquid crystal display device having the liquid crystal composition | CHISSO CORPORATION | 2006-05-11 | — | — | US | disclosed |
| EP-1655360-A1 | Compound having alkyl on benzene ring, liquid crystal compositions having the compound and liquid crystal display device having the liquid crystal composition | CHISSO CORPORATION (JP) | 2006-05-10 | — | — | EP | disclosed |
| US-20060071194-A1 | Tetrahydrofuran compound, liquid crystal, composition and liquid crystal display device containing the liquid crystal composition | JNC PETROCHEMICAL CORPORATION (JP) | 2006-04-06 | — | — | US | disclosed |
| EP-0597701-B1 | Conjugated enyne derivative and liquid crystal composition | CHISSO CORP (JP) | 1997-04-16 | — | — | EP | disclosed |
| EP-0563981-B1 | Cis-1,4-substituted 2-butene derivative | CHISSO CORP (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5401434-A | Cis-1,4-substituted 2-butene derivative | CHISSO CORPORATION (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5370819-A | Low viscosity | CHISSO CORPORATION (JP) | 1994-12-06 | — | — | US | disclosed |
| EP-0597701-A1 | Conjugated enyne derivative and liquid crystal composition | CHISSO CORPORATION (JP) | 1994-05-18 | — | — | EP | disclosed |
| US-4630896-A | Benzonitriles | HOFFMANN-LA ROCHE INC. (US) | 1986-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060097226-A1 | Compound having alkyl on benzene ring, liquid crystal composition having the compound, and liquid crystal display device having the liquid crystal composition | BRD1, CNOT1, CXCR1 | CYP1A2 155/4885PKM 4626/4885MEN1 1895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.