SCHEMBL22109152

SCHEMBL22109152

CP(C)(=O)c1ccc(-c2cnc3nnn(Cc4ccc5ncnn5c4)c3n2)cc1

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MET P08581 20/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12486102 0.85 MET (0.73) MET
SCHEMBL30948861 0.83 MET (0.75) MET
SCHEMBL22109195 0.83 MET (0.57) MET
SCHEMBL22109392 0.83 MET (0.75) MET
SCHEMBL30948874 0.83 MET (0.57) MET
SCHEMBL30948865 0.83 MET (0.57) MET
SCHEMBL12487373 0.83 MET (1.00) MET
SCHEMBL12487193 0.79 MET (0.75) MET
SCHEMBL22109158 0.78 MET (0.59) MET
SCHEMBL12487420 0.78 MET (0.76) MET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3893872-B1 ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF BETA PHARMA INC (US) 2024-07-17 EP disclosed
WO-2020124060-A1 ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF BETA PHARMA, INC. (US) 2020-06-18 WO disclosed