Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16359587 | 0.71 | ATM (0.35) | GPR119NPC1ALDH1A1MAPTKDM4E | |
| SCHEMBL30900387 | 0.68 | KDM4E (0.34) | KMT2AGPR119CHRM2CHRM1CHRM3 | |
| SCHEMBL18071798 | 0.64 | MAPT (0.40) | KMT2AGPR119CHRM2CHRM1CHRM3 | |
| SCHEMBL12852082 | 0.62 | USP2 (0.40) | GLAKMT2AGPR119CHRM2CHRM1 | |
| SCHEMBL11983583 | 0.62 | USP2 (0.40) | GLAKMT2AGPR119CHRM2CHRM1 | |
| SCHEMBL17654928 | 0.62 | GLA (0.37) | GLAKMT2AGPR119CHRM2CHRM1 | |
| SCHEMBL5556528 | 0.61 | MAPT (0.47) | KMT2AGPR119NPC1ALDH1A1MAPT | |
| SCHEMBL28135815 | 0.61 | CHRM2 (0.40) | GLAGPR119CHRM2CHRM1CHRM3 | |
| SCHEMBL30073714 | 0.61 | GLA (0.44) | GLAKMT2AGPR119CHRM2CHRM1 | |
| SCHEMBL30921590 | 0.61 | KDM1A (0.34) | GPR119PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11167048-B2 | Dual targeting ligand for cancer diagnosis and treatment | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2021-11-09 | — | — | US | disclosed |
| US-20200188539-A1 | NOVEL DUAL TARGETING LIGAND FOR CANCER DIAGNOSIS AND TREATMENT | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200188539-A1 | NOVEL DUAL TARGETING LIGAND FOR CANCER DIAGNOSIS AND TREATMENT | KLK3, GRPR, FOLH1 | GLA 1702/4885KMT2A 3061/4885GPR119 36/4885 |
| US-11167048-B2 | Dual targeting ligand for cancer diagnosis and treatment | KLK3, GRPR, FOLH1 | GLA 1127/4885KMT2A 3020/4885GPR119 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.