⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22082598 | 0.80 | — | — | |
| SCHEMBL20937511 | 0.68 | — | — | |
| SCHEMBL22081666 | 0.63 | — | — | |
| SCHEMBL19560716 | 0.62 | — | — | |
| SCHEMBL24782380 | 0.59 | — | — | |
| SCHEMBL974540 | 0.56 | — | — | |
| SCHEMBL22082920 | 0.56 | — | — | |
| SCHEMBL20024636 | 0.55 | — | — | |
| SCHEMBL22360245 | 0.54 | DHFR (0.30) | — | |
| SCHEMBL20686155 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |
| WO-2020124060-A1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA, INC. (US) | 2020-06-18 | — | — | WO | disclosed |