Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14724413 | 0.79 | ALDH1A1 (0.45) | ALDH1A1TSHRKDM4EMAPTL3MBTL1 | |
| SCHEMBL11051238 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TSHRKDM4EMAPTL3MBTL1 | |
| SCHEMBL9955944 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TSHRKDM4EMAPTL3MBTL1 | |
| SCHEMBL11051235 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TSHRKDM4EMAPTL3MBTL1 | |
| SCHEMBL11157395 | 0.75 | RECQL (0.47) | ALDH1A1TSHRRECQLRAB9AHTT | |
| SCHEMBL21568847 | 0.75 | RECQL (0.47) | ALDH1A1TSHRRECQLRAB9AHTT | |
| SCHEMBL16508642 | 0.75 | ALDH1A1 (0.45) | ALDH1A1TSHRKDM4EMAPTL3MBTL1 | |
| SCHEMBL26456891 | 0.74 | ALDH1A1 (0.41) | ALDH1A1TSHRKDM4EMAPTACHE | |
| SCHEMBL27514392 | 0.74 | ALDH1A1 (0.41) | ALDH1A1TSHRKDM4EMAPTL3MBTL1 | |
| SCHEMBL257719 | 0.73 | ALDH1A1 (0.52) | ALDH1A1TSHRKDM4EMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082819-B1 | SUBSTITUTED DIAMINOPYRIMIDYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARM LLC (US) | 2020-06-17 | — | — | EP | disclosed |